PA-23-317: NIH Funding for Expanding Existing Single Project Research Grants

The National Institutes of Health (NIH) has announced a funding opportunity, PA-23-317, aimed at supporting competing revisions to existing NIH single project research grants and cooperative agreements. This discretionary funding instrument spans a wide range of categories, including education, health, and social services, reflecting the diverse nature of NIH-funded research. The opportunity encompasses various research areas, such as human genome research, mental health, cancer detection, and child health and development, among others.

Eligible applicants include a broad spectrum of entities, ranging from educational institutions, government bodies, non-profits, and small businesses, to special district governments and Native American tribal organizations. The primary goal of this funding opportunity is to allow for the expansion of current projects and programs within the awarding NIH Institute or Center, as identified in the competitive revision Notice of Special Interest (NOSI). Applications for these revisions will undergo rigorous scientific and technical merit evaluation by appropriate review groups in accordance with NIH peer review policies and procedures. This initiative represents a significant investment by the NIH in enhancing and broadening the scope of ongoing research projects, contributing to the advancement of knowledge and innovation in critical areas of public health. The closing date for applications is set for January 27, 2026, providing a substantial time frame for researchers to develop and submit their proposals for expanding the impact of their existing projects.