National Institute of Allergy and Infectious Diseases (NIAID) and National Institute of Aging (NIA) Grant: Advancing Understanding of Immunity in Elderly Individuals (R01)

This grant aims to investigate the mechanisms of immunity in the elderly, particularly in response to infections or vaccinations related to NIAID Emerging and Re-emerging Infectious Diseases. The focus is on understanding why elderly individuals experience impaired immune responses and reduced vaccine efficacy. Human studies are required to explore immune changes in the aging population, with the opportunity to include relevant animal research for additional mechanistic insights. Researchers are encouraged to propose projects that will enhance knowledge of immune function in older adults, ultimately leading to improved strategies for combating severe infections and enhancing vaccine responses. Closing date for applications is Feb 20, 2013.

Opportunity ID: 202794

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-AI-12-038
Funding Opportunity Title::	Immunity in the Elderly (R01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.855 — Allergy, Immunology and Transplantation Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Sep 28, 2012
Last Updated Date::
Original Closing Date for Applications::	Feb 20, 2013
Current Closing Date for Applications::	Feb 20, 2013
Archive Date::	Mar 23, 2013
Estimated Total Program Funding::
Award Ceiling::	$300,000
Award Floor::	$

Eligibility

Eligible Applicants::

Special district governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Aging (NIA) invite applications to define the mechanisms for induction, development, and maintenance of protective immunity in the elderly in response to infections with or vaccinations against NIAID Emerging and Re-emerging Infectious Diseases (http://www.niaid.nih.gov/topics/emerging/Pages/list.aspx). The goal of this FOA is to develop a better understanding of the immune mechanisms involved during the aging process that contribute to impaired immune responses resulting in severe infections and dampened responses to vaccines in this population. This FOA requires human studies, to gain insights into immune changes in elderly individuals. Thus, at least one aim of the project must focus fully on human studies; appropriately justified animal work may be included in additional aims to conduct mechanistic studies that are not possible in humans.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	ADOBE-FORMS-B2
Competition Title:	Adobe-Forms-B2
Opportunity Package ID:	PKG00148271
Opening Date:	Jan 18, 2013
Closing Date:	Feb 20, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]