This grant from the Department of Defense aims to support new investigators in the field of Gulf War Illness (GWI) research. It encourages innovative ideas to improve the diagnosis, understanding, and treatment of GWI in Veterans. The award is open to transitioning postdoctoral fellows, early-career investigators, and new researchers in the field. Proposals can focus on biomarker discovery, pathobiology studies, and testing of pharmacologic agents. Collaboration with experienced GWI researchers is encouraged, and projects should have a clear impact on GWI. The grant seeks to advance research on the chronic effects of neurotoxic exposures experienced during the Gulf War, using both clinical and animal models studies. Applications should be submitted by Oct 29, 2015.
Opportunity ID: 276606
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-15-GWIRP-NIA |
| Funding Opportunity Title: | DoD Gulf War Illness New Investigator Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 3 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 14, 2015 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 29, 2015 |
| Current Closing Date for Applications: | Oct 29, 2015 |
| Archive Date: | Nov 28, 2015 |
| Estimated Total Program Funding: | $2,400,000 |
| Award Ceiling: | $0 |
| Award Floor: | $0 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The New Investigator Award mechanism was first offered in FY14. That year, 11 New Investigator Award applications were received, and 4 were recommended for funding. New for FY15: The GWIRP New Investigator Award contains explicit prescriptive language (see below) to guide applicants wishing to propose investigations of potential biomarkers of GWI. The intent of the GWIRP New Investigator Award is to support investigators new to the field of GWI research at different stages of career development. This award enables such investigators to compete for funding separately from investigators with established programs of GWI research. Previous experience in GWI research is allowed, but not required. However, Principal Investigators (PIs) with a limited background in GWI research are strongly encouraged to strengthen their applications through collaboration with investigators who are experienced in GWI research and/or possess other relevant expertise. It is the PI’s responsibility to describe how the collaboration(s) will augment his/her ability to address the research question. All applicants for the New Investigator Award must meet specific eligibility criteria under one of the following categories, as described in Section I.C., Eligibility Information. • Transitioning Postdoctoral Fellow • Early-Career Investigator • New GWI Researcher The New Investigator Award is designed to promote new ideas in GWI research and establish proof-of-principle for further development in future studies. Applications are not required to include preliminary data; however, preliminary data may be used to support the objectives of an application. These data are not required to have come from the GWI research field. Applications not supported by preliminary data should be based on sound scientific rationale and may reflect clinical observations or seek to evaluate discoveries made in relation to other chronic multisymptom illnesses for their application in GWI. Regardless of the approach, the focus should be clearly on Veterans with GWI. It is the responsibility of the PI to clearly and explicitly articulate the project’s potential impact on GWI. The New Investigator Award supports research focusing on the complex of symptoms known as GWI, improving the case definition and diagnosis of GWI, characterizing disease symptoms, and better understanding the pathobiology. The New Investigator Award encourages basic through clinical research aimed at identification of objective measures (e.g., biomarkers) to distinguish healthy Veterans from those with GWI or improve understanding of the pathobiology underlying symptoms associated with GWI. Studies that characterize chronic effects of neurotoxic exposures at dosages comparable to that encountered in-theatre during the Gulf War are of interest. Studies using animal models should focus on long-term and latent effects of toxic exposures to closely represent the current status of GWI patients. All studies using animal models should use an established model unless there is a compelling scientific justification for the development or use of a new model. Development of new animal models is discouraged. The New Investigator Award can also be used for testing of GWI-targeted pharmacologic agents in absorption, distribution, metabolism, and excretion (ADME) studies, and toxicology testing, including Investigational New Drug (IND)-enabling pharmacology/toxicology testing. Preclinical development of non-pharmacological interventions is also acceptable. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk
301-682-5507 Email:help@eBRAP.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 276606 Full Announcement-1 -> gwirp_fy15_nia statement_of_independence_gg.pdf
Folder 276606 Full Announcement-1 -> gwirp_fy15_nia pa_gg.pdf
Folder 276606 Full Announcement-1 -> gwirp_fy15_nia eligibility_statement_gg.pdf
Packages
| Agency Contact Information: | CDMRP Help Desk 301-682-5507 Email: help@eBRAP.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00216896 | May 14, 2015 | Oct 29, 2015 | View |
Package 1
Mandatory forms
276606 RR_SF424_2_0-2.0.pdf
276606 RR_Budget_1_3-1.3.pdf
276606 RR_KeyPersonExpanded_2_0-2.0.pdf
276606 PerformanceSite_2_0-2.0.pdf
Optional forms
276606 RR_SubawardBudget30_1_3-1.3.pdf
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