NIH is offering a grant to investigate the impact of early-life factors on cancer development in adulthood. This grant aims to explore how events and exposures during early life stages influence biological processes relevant to carcinogenesis and to identify predictive markers for cancer risk. Understanding the role of early-life factors in cancer etiology could lead to the development of effective interventions for cancer prevention. The application deadline for this research grant is January 07, 2021.
Opportunity ID: 299568
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-18-532 |
| Funding Opportunity Title: | Early-life Factors and Cancer Development Later in Life (R21 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 20, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2021 |
| Current Closing Date for Applications: | Jan 07, 2021 |
| Archive Date: | Feb 12, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Small businesses State governments City or township governments Special district governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research focused on the role of early-life factors (maternal-paternal, in utero, birth and infancy, puberty, adolescence, and young adult years) in cancer development later in life. Given that the current emerging evidence from limited research indicates a potentially important role for early-life events and exposures in cancer development, it is necessary to better understand 1) the early-life (maternal-paternal, in utero, birth and infancy, puberty, adolescence, and young adult years) factors that are associated with later cancer development; 2) how early-life factors mediate biological processes relevant to carcinogenesis; and 3) whether predictive markers for cancer risk based on what happens biologically at early life can be measured and developed for use in cancer prevention strategies. Markers that predict malignancy or pre-malignant conditions would allow assessment of early-life exposures with relevant outcomes without having to wait decades for cancer development. Ultimately, a better mechanistic understanding of how early-life events and exposures contribute to the etiology of cancer later in life will allow for the development of effective interventions during pregnancy or early life that may have a profound impact on cancer prevention. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-18-532.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E-REVISED | Use for due dates on or before May 24, 2020 | PKG00237419 | Jan 16, 2018 | May 24, 2020 | View | |
| FORMS-E | Posted incorrectly. Must use FORMS-E-REVISED package | PKG00237180 | Jan 05, 2018 | Jan 06, 2018 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259977 | Jan 16, 2018 | Jan 07, 2021 | View |
Package 1
Mandatory forms
299568 RR_SF424_2_0-2.0.pdf
299568 PHS398_CoverPageSupplement_4_0-4.0.pdf
299568 RR_OtherProjectInfo_1_4-1.4.pdf
299568 PerformanceSite_2_0-2.0.pdf
299568 RR_KeyPersonExpanded_2_0-2.0.pdf
299568 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
299568 RR_Budget_1_4-1.4.pdf
299568 RR_SubawardBudget30_1_4-1.4.pdf
299568 PHS398_ModularBudget_1_2-1.2.pdf
299568 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
299568 RR_SF424_2_0-2.0.pdf
299568 PHS398_CoverPageSupplement_4_0-4.0.pdf
299568 RR_OtherProjectInfo_1_4-1.4.pdf
299568 PerformanceSite_2_0-2.0.pdf
299568 RR_KeyPersonExpanded_2_0-2.0.pdf
299568 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
299568 PHS_Additional_IndirectCosts-1.0.pdf
299568 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 3
Mandatory forms
299568 RR_SF424_2_0-2.0.pdf
299568 PHS398_CoverPageSupplement_5_0-5.0.pdf
299568 RR_OtherProjectInfo_1_4-1.4.pdf
299568 PerformanceSite_2_0-2.0.pdf
299568 RR_KeyPersonExpanded_2_0-2.0.pdf
299568 PHS398_ResearchPlan_4_0-4.0.pdf
299568 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
299568 RR_Budget_1_4-1.4.pdf
299568 RR_SubawardBudget30_1_4-1.4.pdf
299568 PHS398_ModularBudget_1_2-1.2.pdf
299568 PHS_AssignmentRequestForm_3_0-3.0.pdf
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