Opportunity ID: 299628

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 5
Posted Date: Dec 21, 2017
Last Updated Date: Feb 20, 2018
Original Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Current Closing Date for Applications: Feb 22, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 24, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:
Component A. BD-STEPS II CORE recipient:

Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015 or 2016, and race/ethnic distribution.
Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.
Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program.

Component B. BD-STEPS Stillbirth recipient:

Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015 or 2016, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.
The activities under this NOFO will be supported by two separate but related funding components:
Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.

Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

Version History

Version Modification Description Updated Date
NOFO to include Q and A’s. Feb 20, 2018
February 2, 2018
ACTION ITEM:

The application package for this NOFO has been revised to comply with form compatibility at Grants.gov and eRA Commons.

All applicants are required to go to Grants.gov and retrieve the revised application package in order for it to pass, Grants.gov and eRA Commons validation.

If you have any questions please contact OGSTIMS for assistance.
Email address: ogstims@cdc.gov phone number: 770-488-2700

Feb 20, 2018
February 2, 2018

ACTION ITEM:

The application package for this NOFO has been revised to comply with form compatibility at Grants.gov and eRA Commons.

All applicants are required to go to Grants.gov and retrieve the revised application package in order for it to pass, Grants.gov and eRA Commons validation.

If you have any questions please contact OGSTIMS for assistance.
Email address: ogstims@cdc.gov phone number: 770-488-2700

Feb 02, 2018
Updated the application Package with FORMS-E R&R Senior/Key Person Profile (Expanded) forms. L.C. Browning Feb 02, 2018
Jan 05, 2018

DISPLAYING: Synopsis 5

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 5
Posted Date: Dec 21, 2017
Last Updated Date: Feb 20, 2018
Original Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Current Closing Date for Applications: Feb 22, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 24, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:
Component A. BD-STEPS II CORE recipient:

Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015 or 2016, and race/ethnic distribution.
Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.
Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program.

Component B. BD-STEPS Stillbirth recipient:

Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015 or 2016, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.
The activities under this NOFO will be supported by two separate but related funding components:
Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.

Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

DISPLAYING: Synopsis 4

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 4
Posted Date: Feb 20, 2018
Last Updated Date: Feb 02, 2018
Original Closing Date for Applications:
Current Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 22, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:Component A. BD-STEPS II CORE recipient:Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution.Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program. Component B. BD-STEPS Stillbirth recipient:Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.The activities under this NOFO will be supported by two separate but related funding components:Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component. Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

DISPLAYING: Synopsis 3

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 3
Posted Date: Feb 02, 2018
Last Updated Date: Feb 02, 2018
Original Closing Date for Applications:
Current Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 22, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:Component A. BD-STEPS II CORE recipient:Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution.Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program. Component B. BD-STEPS Stillbirth recipient:Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.The activities under this NOFO will be supported by two separate but related funding components:Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component. Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Feb 02, 2018
Last Updated Date: Jan 05, 2018
Original Closing Date for Applications:
Current Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 22, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:Component A. BD-STEPS II CORE recipient:Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution.Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program. Component B. BD-STEPS Stillbirth recipient:Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.The activities under this NOFO will be supported by two separate but related funding components:Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component. Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-DD-18-001
Funding Opportunity Title: Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 6
Assistance Listings: 93.073 — Birth Defects and Developmental Disabilities – Prevention and Surveillance
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Jan 05, 2018
Last Updated Date:
Original Closing Date for Applications:
Current Closing Date for Applications: Feb 20, 2018 Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.
Archive Date: Mar 22, 2018
Estimated Total Program Funding: $28,500,000
Award Ceiling: $1,100,000
Award Floor: $700,000

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility: For an application to be considered, it must be responsive to the following special eligibility requirements:
Component A. BD-STEPS II CORE recipient:

Access to a pre-existing population-based birth defects surveillance system that can provide data on all birth defects listed in Table 1 and access to necessary data sources to ascertain liveborn control infants (i.e. vital records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area which has to include 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution.
Evidence of legal access to the birth defects surveillance system is required. If the applicant is not a State health department, inclusion of a letter or memorandum of understanding from the State health department confirming the applicant has access to the necessary data sources in order to ascertain case and control subjects.
Access to the state’s National Electronic Disease Surveillance (NEDS) system for ascertainment of reportable infections as evidenced by a letter of support from the State’s NEDS program.

Component B. BD-STEPS Stillbirth recipient:

Access to necessary data sources to ascertain stillborn infants (i.e. fetal death records or birth hospital records) as evidenced by a letter from the State health department or other State or private organization.
Description of the selected birth population and geographic area that includes 30,000 – 75,000 births annually as evidenced by a table listing the counties in the covered area, number of births in 2015, and race/ethnic distribution. This area has to be the same geographical area as described for Component A.

Additional Information

Agency Name: Centers for Disease Control and Prevention – ERA
Description: CDC has previously implemented population based case control studies of birth defects known as the National Birth Defects Prevention Study (NBDPS) for births from 1997-2011 and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS I) which started with births in 2014 and is ongoing. The purpose of BD-STEPS II is to identify causes of birth defects and stillbirths using epidemiologic and genetic research methods and provide information that could be translated into public health prevention messages.
The activities under this NOFO will be supported by two separate but related funding components:
Component A. BD-STEPS II Core. To support the epidemiological and genetic research capability of the Centers for Birth Defects Research and Prevention (CBDRP) through BD-STEPS. The intent of this BD-STEPS II is to carry out BD-STEPS using the same basic study design currently used by grantees with a focus on the key areas of: (1) maternal chronic diseases and their treatments; (2) infectious disease in pregnancy; and (3) medications. In BD-STEPS II, we will add focus on infectious causes of birth defects, and pilots will be conducted to determine feasibility of medication use validation. Both new sites and current BD-STEPS sites are encouraged to apply for this component.
Component B. BD-STEPS stillbirth. To support the exploration of modifiable risk factors for stillbirths. The intent of this component is to conduct a case-control study of stillbirth risk factors using the BD-STEPS II Core interview and a follow-up interview with mothers affected by stillbirths and mothers of livebirths. To be funded for Component B, applicants must have a responsive application for Component A and receive Component A funding. Both new sites and current BD-STEPS sites are encouraged to apply for this component.

Link to Additional Information:
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

Marcela Law
mah7@cdc.gov

Email:mah7@cdc.gov

Folder 299628 Full Announcement-FULL_ANNOUNCEMENT -> RFA-DD18-001AmendmentPublication.pdf

Folder 299628 Other Supporting Documents-APPLICATION PACKAGE UPDATE -> ACTION ITEM.pdf

Packages

Agency Contact Information: Marcela Law
mah7@cdc.gov

Email: mah7@cdc.gov

Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
93.073 RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS) II PKG00237257 Dec 21, 2017 Feb 22, 2018 View

Package 1

Mandatory forms

299628 RR_SF424_2_0-2.0.pdf

299628 RR_Budget_1_4-1.4.pdf

299628 PHS398_ResearchPlan_4_0-4.0.pdf

299628 PHS398_CoverPageSupplement_4_0-4.0.pdf

299628 RR_OtherProjectInfo_1_4-1.4.pdf

299628 PerformanceSite_2_0-2.0.pdf

299628 RR_KeyPersonExpanded_2_0-2.0.pdf

Optional forms

299628 RR_SubawardBudget30_1_4-1.4.pdf

2025-07-09T08:58:56-05:00

Share This Post, Choose Your Platform!

About the Author: