The National Institute on Alcohol Abuse and Alcoholism (NIAAA) is offering a grant to support research on the molecular and cellular mechanisms of tissue injury and repair caused by alcohol use. This grant aims to investigate how excessive alcohol consumption affects various organ systems and impairs the body’s ability to recover from trauma. Researchers are encouraged to explore the impact of alcohol on stem cells, embryonic development, and regeneration, as well as the effects of moderate alcohol consumption. By gaining insights into these mechanisms, new strategies for diagnosing and treating alcohol-induced organ damage may be developed. Closing date for applications is May 07, 2017.
Opportunity ID: 251977
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-14-123 |
| Funding Opportunity Title: | Alcohol-Induced Effects on Tissue Injury and Repair (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 28, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 07, 2017 |
| Current Closing Date for Applications: | May 07, 2017 |
| Archive Date: | Jun 07, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Private institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments City or township governments Small businesses Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages Research Project Grant (R01) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for recovery and repair following trauma. The mechanisms for these alcohol-induced effects on tissue injury and repair are currently not fully understood. NIAAA is especially interested in integrative research that elucidates alcohols effects on complex mechanisms of injury and repair that are either common or specific to each organ system. This FOA also encourages the study of alcohols effect on stem cells, embryonic development, and regeneration. Also encourages are studies on molecular and cellular actions of moderate alcohol consumption. A better understanding of these underlying mechanisms may provide new avenues for developing more effective and novel approaches for prognosis, diagnosis, intervention, and treatment of alcohol-induced organ damage. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-14-123.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.273 | FORMS-C | Forms-C | PKG00193415 | May 05, 2014 | May 07, 2016 | View |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222019 | Apr 17, 2016 | May 07, 2017 | View |
Package 1
Mandatory forms
251977 RR_SF424_2_0-2.0.pdf
251977 PHS398_ResearchPlan_2_0-2.0.pdf
251977 PHS398_CoverPageSupplement_2_0-2.0.pdf
251977 RR_KeyPersonExpanded_2_0-2.0.pdf
251977 RR_OtherProjectInfo_1_3-1.3.pdf
251977 PerformanceSite_2_0-2.0.pdf
Optional forms
251977 RR_SubawardBudget30_1_3-1.3.pdf
251977 PlannedReport-1.0.pdf
251977 PHS398_CumulativeInclusionReport-1.0.pdf
251977 PHS398_ModularBudget_1_2-1.2.pdf
251977 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
251977 RR_SF424_2_0-2.0.pdf
251977 PHS398_CoverPageSupplement_3_0-3.0.pdf
251977 RR_OtherProjectInfo_1_3-1.3.pdf
251977 PerformanceSite_2_0-2.0.pdf
251977 RR_KeyPersonExpanded_2_0-2.0.pdf
251977 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
251977 RR_Budget_1_3-1.3.pdf
251977 RR_SubawardBudget30_1_3-1.3.pdf
251977 PHS398_ModularBudget_1_2-1.2.pdf
251977 PHS_Inclusion_Enrollment_Report-1.0.pdf
251977 PHS_AssignmentRequestForm-1.0.pdf
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