The Health Department is offering a Research Grant to continue follow-up of the Diabetes Prevention Program Outcomes Study (DPPOS) cohort, focusing on the effectiveness of early metformin treatment in preventing cardiovascular disease and cancer development. The grant aims to build upon the findings of the Diabetes Prevention Program (DPP) and DPPOS, emphasizing the long-term effects of interventions on diabetes development and microvascular complications. Researchers will collaborate through a cooperative agreement to further understand the impact of lifestyle changes and metformin in reducing the risk of type 2 diabetes. Application deadline: May 28, 2014.
Opportunity ID: 252437
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-14-501 |
| Funding Opportunity Title: | Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | 23 |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 12, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 28, 2014 |
| Current Closing Date for Applications: | May 28, 2014 |
| Archive Date: | Jun 28, 2014 |
| Estimated Total Program Funding: | $10,000,000 |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Limited Competition Funding Opportunity Announcement (FOA) is to continue follow-up of the Diabetes Prevention Program Outcomes Study (DPPOS) cohort through a cooperative agreement. The Diabetes Prevention Program (DPP) was a multi-center controlled clinical trial examining the efficacy of treatments to prevent or delay the development of type 2 diabetes in a population at high risk. The DPP demonstrated that either lifestyle change or the drug metformin could reduce the development of type 2 diabetes by 58% and 31%, respectively, compared with placebo. Following the end of DPP, the DPP cohort was enrolled in the DPPOS to determine the long-term effects of the DPP interventions on further diabetes development and microvascular complications. The primary purpose of this FOA is to continue follow-up of the DPPOS cohort to examine the effectiveness of early metformin treatment on the development of cardiovascular disease and cancer. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-14-501.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.847 | FORMS-C | Forms-C | PKG00193873 | Apr 28, 2014 | May 28, 2014 | View |
Package 1
Mandatory forms
252437 RR_SF424_2_0-2.0.pdf
252437 PHS398_ResearchPlan_2_0-2.0.pdf
252437 PHS398_CoverPageSupplement_2_0-2.0.pdf
252437 RR_KeyPersonExpanded_2_0-2.0.pdf
252437 RR_OtherProjectInfo_1_3-1.3.pdf
252437 PerformanceSite_2_0-2.0.pdf
Optional forms
252437 RR_SubawardBudget30_1_3-1.3.pdf
252437 PlannedReport-1.0.pdf
252437 PHS398_CumulativeInclusionReport-1.0.pdf
252437 PHS398_ModularBudget_1_2-1.2.pdf
252437 RR_Budget_1_3-1.3.pdf
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