This grant aims to investigate how neurophysiological patterns can be targeted to improve cognitive deficits in brain disorders. Researchers are encouraged to modify electrophysiological patterns during behavior to enhance cognitive abilities. The initiative seeks studies that explore neural coordination parameters, cellular abnormalities’ effects on electrophysiological patterns, predict electrophysiological changes in humans, and develop computational models to understand these patterns. Applications are open until May 07, 2017, 12:00:00 AM EDT for experimental designs addressing these critical topics.
Opportunity ID: 252518
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-14-153 |
| Funding Opportunity Title: | Temporal Dynamics of Neurophysiological Patterns as Potential Targets for Treating Cognitive Deficits in Brain Disorders (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 14, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | May 07, 2017 |
| Current Closing Date for Applications: | May 07, 2017 |
| Archive Date: | Jun 07, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments State governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Special district governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education County governments Independent school districts Small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | A rich body of evidence suggests that cognitive processes are associated with particular patterns of neural activity. These data indicate that oscillatory rhythms, their co-modulation across frequency bands, spike-phase correlations, spike population dynamics, and other patterns might be useful drivers of therapeutic development for cognitive improvement in neuropsychiatric disorders. This initiative encourages applications to test whether modifying electrophysiological patterns during behavior can improve cognitive abilities. Applications should use experimental designs that incorporate active manipulations to address at least one, and ideally more, of the following topics: (1) in behaving animals, determine which parameters of neural coordination, when manipulated in isolation, improve particular aspects of cognition; (2) in animals or humans, determine how particular abnormalities at the cellular or molecular level, such as specific receptor dysfunction, affect the coordination of electrophysiological patterns during behavior; (3) determine whether in vivo, systems-level electrophysiological changes in behaving animals predict analogous electrophysiological and cognitive improvements in normal humans or clinical populations; and (4) use systems-level computational modeling to develop a principled understanding of the function and mechanisms by which oscillatory and other electrophysiological temporal dynamic patterns unfold across the brain (cortically and subcortically) to impact cognition. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-14-153.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | Forms-C | PKG00193956 | May 05, 2014 | May 07, 2016 | View | |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222067 | Apr 17, 2016 | May 07, 2017 | View |
Package 1
Mandatory forms
252518 RR_SF424_2_0-2.0.pdf
252518 PHS398_ResearchPlan_2_0-2.0.pdf
252518 PHS398_CoverPageSupplement_2_0-2.0.pdf
252518 RR_KeyPersonExpanded_2_0-2.0.pdf
252518 RR_OtherProjectInfo_1_3-1.3.pdf
252518 PerformanceSite_2_0-2.0.pdf
Optional forms
252518 RR_SubawardBudget30_1_3-1.3.pdf
252518 PlannedReport-1.0.pdf
252518 PHS398_CumulativeInclusionReport-1.0.pdf
252518 PHS398_ModularBudget_1_2-1.2.pdf
252518 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
252518 RR_SF424_2_0-2.0.pdf
252518 PHS398_CoverPageSupplement_3_0-3.0.pdf
252518 RR_OtherProjectInfo_1_3-1.3.pdf
252518 PerformanceSite_2_0-2.0.pdf
252518 RR_KeyPersonExpanded_2_0-2.0.pdf
252518 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
252518 RR_Budget_1_3-1.3.pdf
252518 RR_SubawardBudget30_1_3-1.3.pdf
252518 PHS398_ModularBudget_1_2-1.2.pdf
252518 PHS_Inclusion_Enrollment_Report-1.0.pdf
252518 PHS_AssignmentRequestForm-1.0.pdf
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