This grant offered by the NIH HEAL Initiative focuses on exploring how sleep and circadian mechanisms contribute to opiate use disorder (OUD), withdrawal, and medication-assisted treatment (MAT) response. Applicants are encouraged to conduct clinical studies to advance understanding in these areas and propose multi-disciplinary teams with various expertise. The aim is to utilize findings in sleep and circadian biology to enhance OUD therapy. Proposals must focus on investigating OUD-related mechanisms and pathobiology, avoiding interventions without a strong mechanistic study design. Closing date for applications is February 27, 2019.
Opportunity ID: 310980
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-19-029 |
| Funding Opportunity Title: | HEAL Initiative: Sleep and Circadian-Dependent Mechanisms Contributing to Opiate Use Disorder (OUD) and Response to Medication Assisted Treatment (MAT) (U01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 10, 2018 |
| Last Updated Date: | Dec 10, 2018 |
| Original Closing Date for Applications: | Feb 27, 2019 |
| Current Closing Date for Applications: | Feb 27, 2019 |
| Archive Date: | Apr 04, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses County governments Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites clinical studies to elucidate sleep and circadian mechanisms that contribute to the risk of opiate use disorder (OUD), the pathobiology of opiate withdrawal, and that influence the response to medication-assisted treatment (MAT). Studies are needed to apply advances in understanding sleep and circadian biology to improving our understanding of OUD, the directionality of sleep and OUD interactions, and the opportunities to improve therapy and outcome. Multi-disciplinary, multiple-investigator teams combining expertise in clinical research, mechanisms of sleep and circadian rhythms, neurobiology of OUD, and neuropharmacology of MAT are strongly encouraged. This FOA is only open to the study of OUD relevant mechanisms and pathobiology. Evaluating the efficacy of one or more interventions without a rigorous mechanistic study design should not be proposed. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-19-029.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00246768 | Jan 27, 2019 | Feb 27, 2019 | View |
Package 1
Mandatory forms
310980 RR_SF424_2_0-2.0.pdf
310980 PHS398_CoverPageSupplement_4_0-4.0.pdf
310980 RR_OtherProjectInfo_1_4-1.4.pdf
310980 PerformanceSite_2_0-2.0.pdf
310980 RR_KeyPersonExpanded_2_0-2.0.pdf
310980 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
310980 RR_Budget_1_4-1.4.pdf
310980 RR_SubawardBudget30_1_4-1.4.pdf
310980 PHS398_ModularBudget_1_2-1.2.pdf
310980 PHS_AssignmentRequestForm_2_0-2.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
