This grant from the National Institutes of Health (NIH) focuses on examining the role of sleep and circadian mechanisms in opiate use disorder (OUD) and the response to medication-assisted treatment (MAT). Researchers will investigate how these mechanisms contribute to the risk of OUD, the pathobiology of opiate withdrawal, and the effectiveness of MAT. Interdisciplinary teams with expertise in sleep and circadian biology, OUD, and MAT are encouraged to apply. Studies must solely focus on OUD mechanisms and pathobiology. This opportunity aims to advance understanding and enhance therapy outcomes for OUD. Closing date for applications is February 27, 2019.
Opportunity ID: 310985
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-19-028 |
| Funding Opportunity Title: | HEAL Initiative: Sleep and Circadian-Dependent Mechanisms Contributing to Opiate Use Disorder (OUD) and Response to Medication Assisted Treatment (MAT) (R01 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.233 — National Center on Sleep Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 10, 2018 |
| Last Updated Date: | Dec 10, 2018 |
| Original Closing Date for Applications: | Feb 27, 2019 |
| Current Closing Date for Applications: | Feb 27, 2019 |
| Archive Date: | Apr 04, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $350,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Special district governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA aims to elucidate basic sleep and circadian mechanisms contributing to the risk of opiate use disorder (OUD), the pathobiology of opiate withdrawal, and that influence the response to medication-assisted treatment (MAT). Studies are needed to apply advances in understanding sleep and circadian biology to improving our understanding of OUD, the directionality of sleep and OUD interactions, and the opportunities to improve therapy and outcome. Multi-disciplinary, multiple-investigator teams combining expertise in sleep and circadian neurobiology with the neurobiology OUD and pharmacology of MAT are strongly encouraged. This FOA is only open to the study of OUD relevant mechanisms and pathobiology. The study of other drugs of abuse will not be responsive. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-19-028.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00246772 | Jan 27, 2019 | Feb 27, 2019 | View |
Package 1
Mandatory forms
310985 RR_SF424_2_0-2.0.pdf
310985 PHS398_CoverPageSupplement_4_0-4.0.pdf
310985 RR_OtherProjectInfo_1_4-1.4.pdf
310985 PerformanceSite_2_0-2.0.pdf
310985 RR_KeyPersonExpanded_2_0-2.0.pdf
310985 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
310985 RR_Budget_1_4-1.4.pdf
310985 RR_SubawardBudget30_1_4-1.4.pdf
310985 PHS398_ModularBudget_1_2-1.2.pdf
310985 PHS_AssignmentRequestForm_2_0-2.0.pdf
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