The Department of Health & Human Services is offering the Molecular Imaging of the Lung – Phase 2 Grant (R01) for the development of novel in vivo imaging technologies targeting pulmonary disease pathways. This grant aims to enable early detection and diagnosis of lung diseases, noninvasive monitoring, and advancements in cell-specific drug delivery. Phase 2 seeks to translate research from animal models to human lung diseases, encompassing in vivo studies with appropriate animal models and human tissues/cells. Applicants can conduct Investigational New Drug (IND)-enabling studies. Funding is open to all, regardless of previous Phase 1 funding.
Opportunity ID: 275244
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HL-16-001 |
| Funding Opportunity Title: | Molecular Imaging of the Lung – Phase 2 (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 5 |
| Assistance Listings: | 93.838 — Lung Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 17, 2015 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 15, 2015 |
| Current Closing Date for Applications: | Jun 15, 2015 |
| Archive Date: | Jul 16, 2015 |
| Estimated Total Program Funding: | $3,500,000 |
| Award Ceiling: | $450,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Independent school districts Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) County governments Small businesses Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites Research Project Grant (R01) applications to develop novel in vivo imaging technologies using molecular probes that target pathways or cells involved in the pathobiology of pulmonary diseases. The long-term goal of this program is to develop novel molecular imaging entities and approaches that facilitate early detection and diagnosis of lung disease, enable noninvasive monitoring of lung disease progression and prognosis, and accelerate progress of cell-specific drug delivery and therapies.The previous FOA (RFA-HL-12-036 – Phase 1) supported projects to develop and validate innovative novel imaging agents and approaches that included target selection, probe development and production, and initial characterization of the probe. Phase 2 of this initiative will support studies that advance translation of identified probes and associated imaging approaches from animal models into applicability for human lung diseases. Phase 2 studies must include work performed in vivo using appropriate animal models of lung diseaseand studies using human tissues and/or cells. Applications proposing Investigational New Drug (IND)-enabling studies of novel probes and imaging approaches are encouraged. Applicants are not required to have been funded in Phase 1 (RFA-HL-12-036) in order to submit applications for Phase 2. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-16-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00215603 | May 15, 2015 | Jun 15, 2015 | View |
Package 1
Mandatory forms
275244 RR_SF424_2_0-2.0.pdf
275244 PHS398_ResearchPlan_2_0-2.0.pdf
275244 PHS398_CoverPageSupplement_2_0-2.0.pdf
275244 RR_KeyPersonExpanded_2_0-2.0.pdf
275244 RR_OtherProjectInfo_1_3-1.3.pdf
275244 PerformanceSite_2_0-2.0.pdf
Optional forms
275244 RR_SubawardBudget30_1_3-1.3.pdf
275244 PlannedReport-1.0.pdf
275244 PHS398_CumulativeInclusionReport-1.0.pdf
275244 PHS398_ModularBudget_1_2-1.2.pdf
275244 RR_Budget_1_3-1.3.pdf
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