The National Institutes of Health is offering the TaRGET II grant to establish a consortium exploring the conservation of epigenomic mark perturbations across tissues/cells and surrogate models in mice for environmentally relevant diseases. This grant aims to provide insights for human studies where accessing target tissues is challenging. Closing date for applications is June 24, 2015.
Opportunity ID: 275688
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-15-001 |
| Funding Opportunity Title: | TaRGET II: Environmental Epigenomic Analysis in Tissue Surrogates (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 07, 2015 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 24, 2015 |
| Current Closing Date for Applications: | Jun 24, 2015 |
| Archive Date: | Jul 25, 2015 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Special district governments Small businesses Private institutions of higher education State governments Public and State controlled institutions of higher education Independent school districts Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Environmental exposure induced perturbations of epigenomic marks are correlated with disease pathogenesis.Identifying changes in epigenomic marks (e.g., DNA methylation, histone modifications, chromatin accessibility) in affected tissues/cells is not always feasible in humans. The purpose of this Funding Opportunity Announcement (FOA) is to establish a consortium that will explore the conservation of perturbations of epigenomic marks across target tissues/cells and surrogate tissues/cells using mouse models of environmentally relevant diseases. Ultimately, these analyses will provide insights into the design and interpretation of human studies where target tissues are inaccessible. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-001.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00216037 | May 24, 2015 | Jun 24, 2015 | View |
Package 1
Mandatory forms
275688 RR_SF424_2_0-2.0.pdf
275688 PHS398_ResearchPlan_2_0-2.0.pdf
275688 PHS398_CoverPageSupplement_2_0-2.0.pdf
275688 RR_KeyPersonExpanded_2_0-2.0.pdf
275688 RR_OtherProjectInfo_1_3-1.3.pdf
275688 PerformanceSite_2_0-2.0.pdf
Optional forms
275688 RR_SubawardBudget30_1_3-1.3.pdf
275688 PlannedReport-1.0.pdf
275688 PHS398_CumulativeInclusionReport-1.0.pdf
275688 PHS398_ModularBudget_1_2-1.2.pdf
275688 RR_Budget_1_3-1.3.pdf
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