This grant offered by the National Cancer Institute aims to support projects focusing on developing new targeted therapies for oral cancer by identifying and targeting co-dependent survival and proliferation pathways. It encourages collaboration among cancer biologists, computational biologists, model system specialists, and screening assay specialists to explore potential signaling pathways for combination therapy approaches. The emphasis is on the conceptual phase of target identification and proof-of-concept exploration. The closing date for submissions is August 25, 2014.
Opportunity ID: 254151
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DE-15-004 |
| Funding Opportunity Title: | Targeting Co-dependent Molecular Pathways in Oral Cancer (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 22, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Aug 25, 2014 |
| Current Closing Date for Applications: | Aug 25, 2014 |
| Archive Date: | Sep 25, 2014 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $600,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses State governments Native American tribal governments (Federally recognized) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support multi-disciplinary projects aimed at the development of new targeted and effective therapies through systematic use and leveraging of recently identified genomic abnormalities and attendant changes in gene and/or protein expression profiles in human oral cancer samples. The goal of the FOA is the identification of co-dependent survival and proliferation pathways in oral cancer cells and the elucidation of potential signaling pathways that can be targeted with combination therapy approaches. This initiative requires collaboration of multi-disciplinary research teams that include cancer biologists, computational biologists, model system specialists and/or screening assay specialists. The emphasis will be on the conceptual phase of target identification and exploration including proof-of-concept phase. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DE-15-004.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | Forms-C | PKG00195586 | Jul 25, 2014 | Aug 25, 2014 | View |
Package 1
Mandatory forms
254151 RR_SF424_2_0-2.0.pdf
254151 PHS398_ResearchPlan_2_0-2.0.pdf
254151 PHS398_CoverPageSupplement_2_0-2.0.pdf
254151 RR_KeyPersonExpanded_2_0-2.0.pdf
254151 RR_OtherProjectInfo_1_3-1.3.pdf
254151 PerformanceSite_2_0-2.0.pdf
Optional forms
254151 RR_SubawardBudget30_1_3-1.3.pdf
254151 PlannedReport-1.0.pdf
254151 PHS398_CumulativeInclusionReport-1.0.pdf
254151 PHS398_ModularBudget_1_2-1.2.pdf
254151 RR_Budget_1_3-1.3.pdf
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