The NIEHS is offering the FRAMED grant to fund R21 applications focusing on the impact of environmental exposures on RNA modifications. This grant aims to support innovative research that explores how stressors induce changes in RNA modifications, affecting cellular regulation. Applications should propose high risk, high reward research to advance our understanding of epitranscriptomics in response to environmental influences. Closing date for submissions is May 16, 2019.
Opportunity ID: 312740
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-19-002 |
| Funding Opportunity Title: | Functional RNA Modifications Environment and Disease (FRAMED) (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | 4 |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 08, 2019 |
| Last Updated Date: | Feb 08, 2019 |
| Original Closing Date for Applications: | May 16, 2019 |
| Current Closing Date for Applications: | May 16, 2019 |
| Archive Date: | Jun 21, 2019 |
| Estimated Total Program Funding: | $1,000,000 |
| Award Ceiling: | $150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Special district governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments County governments For profit organizations other than small businesses State governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Chemical modifications of proteins, DNA and RNA nucleoside moieties play critical roles in regulating gene expression. Emerging evidence suggests these RNA modifications (epitranscriptomics) have substantive roles in basic biological processes. Recent studies in yeast, Drosophila and rodent models demonstrate stressors can induce RNA modifications, with specific epitranscriptomic reprogramming of some regulatory RNAs. The purpose of the eFRAMED FOA is to solicit and support R21 applications that propose conducting innovative, high risk, high reward research to enhance our understanding of how environmental exposures impact this layer of cellular regulation. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-19-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00248168 | Apr 16, 2019 | May 16, 2019 | View |
Package 1
Mandatory forms
312740 RR_SF424_2_0-2.0.pdf
312740 PHS398_CoverPageSupplement_4_0-4.0.pdf
312740 RR_OtherProjectInfo_1_4-1.4.pdf
312740 PerformanceSite_2_0-2.0.pdf
312740 RR_KeyPersonExpanded_2_0-2.0.pdf
312740 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
312740 RR_Budget_1_4-1.4.pdf
312740 RR_SubawardBudget30_1_4-1.4.pdf
312740 PHS398_ModularBudget_1_2-1.2.pdf
312740 PHS_AssignmentRequestForm_2_0-2.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
