This grant from the National Institutes of Health supports the use of Collaborative Cross (CC) mouse lines to study host genetics in immune regulation. It aims to develop CC mouse lines mirroring human immune responses and investigates areas like immune system function, response to pathogens/vaccines, and mechanisms of immune-mediated diseases. Research under this grant will focus on immune system development, host susceptibility to pathogens, and immune mechanisms in disease development and progression, including autoimmunity and inflammation. Applications for this grant are open until September 9, 2020.
Opportunity ID: 305017
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-18-781 |
| Funding Opportunity Title: | Collaborative Cross (CC) Mouse Model Generation and Discovery of Immunoregulatory Mechanisms (R21 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 11, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 09, 2020 |
| Current Closing Date for Applications: | Sep 09, 2020 |
| Archive Date: | Oct 15, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Independent school districts Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments For profit organizations other than small businesses Public housing authorities/Indian housing authorities City or township governments State governments County governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to support the use of Collaborative Cross (CC) mouse lines to advance understanding of the host genetics involved in immune regulation and function and to further develop CC mouse lines that more faithfully reproduce human immune responses. Research areas supported by this FOA include: immune system development, function or regulation; mechanisms governing immune response to infectious pathogens, vaccines or adjuvants; host susceptibility factors and mechanisms of pathogen-induced immunopathology; and immune mechanisms involved in the development and progression of immune-mediated diseases, such as allergy/asthma, autoimmunity, primary immunodeficiency, inflammation, and cell/organ/tissue transplant rejection or tolerance. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-18-781.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00242003 | Aug 04, 2018 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259962 | Aug 04, 2018 | Sep 09, 2020 | View |
Package 1
Mandatory forms
305017 RR_SF424_2_0-2.0.pdf
305017 PHS398_CoverPageSupplement_4_0-4.0.pdf
305017 RR_OtherProjectInfo_1_4-1.4.pdf
305017 PerformanceSite_2_0-2.0.pdf
305017 RR_KeyPersonExpanded_2_0-2.0.pdf
305017 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
305017 RR_Budget_1_4-1.4.pdf
305017 RR_SubawardBudget30_1_4-1.4.pdf
305017 PHS398_ModularBudget_1_2-1.2.pdf
305017 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
305017 RR_SF424_2_0-2.0.pdf
305017 PHS398_CoverPageSupplement_5_0-5.0.pdf
305017 RR_OtherProjectInfo_1_4-1.4.pdf
305017 PerformanceSite_2_0-2.0.pdf
305017 RR_KeyPersonExpanded_2_0-2.0.pdf
305017 PHS398_ResearchPlan_4_0-4.0.pdf
305017 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
305017 RR_Budget_1_4-1.4.pdf
305017 RR_SubawardBudget30_1_4-1.4.pdf
305017 PHS398_ModularBudget_1_2-1.2.pdf
305017 PHS_AssignmentRequestForm_3_0-3.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
