The National Institute on Aging is offering a grant to institutions/organizations to study the molecular mechanisms controlling circadian clocks in aging tissues, focusing on peripheral and extra suprachiasmatic nucleus clocks. Research will explore the impact of clock system alterations on chromatin remodeling, gene expression, translation, signaling, and cell function. Priority will be given to investigating the pathophysiology of circadian clock regulation changes in aged tissues in response to metabolic/nutritional, environmental, and pharmacological factors. Application deadline is Nov 07, 2012.
Opportunity ID: 192994
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-AG-13-007 |
| Funding Opportunity Title:: | Molecular Mechanisms of Circadian Clocks in Aging Tissues (R01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 2 |
| Posted Date:: | Aug 16, 2012 |
| Last Updated Date:: | Aug 16, 2012 |
| Original Closing Date for Applications:: | Nov 07, 2012 |
| Current Closing Date for Applications:: | Nov 07, 2012 |
| Archive Date:: | Dec 08, 2012 |
| Estimated Total Program Funding:: | $ 1,500,000 |
| Award Ceiling:: | $200,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | This FOA issued by the National Institute on Aging (NIA), National Institutes of Health (NIH), solicits grant applications from institutions/organizations that propose research to enhance the understanding of the molecular mechanisms that control circadian clocks in aging tissues.This FOA encourages studies on the roles of peripheral and extra suprachiasmatic nucleus (SCN) circadian clocks during aging.These studies include understanding the impact of alterations in the clock system on chromatin remodeling, gene expression, translation, signaling, and function of individual cells.In addition, studies are solicited on the pathophysiology of alterations to circadian clock regulation in aged tissues, with particular attention to the response of the clock system to metabolic/nutritional, environmental and pharmacological challenges. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 2 | Updated to add the Estimated Total Program Funding amount. | Aug 16, 2012 |
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | Adobe-Forms-B2 |
| Opportunity Package ID: | PKG00139230 |
| Opening Date: | Oct 05, 2012 |
| Closing Date: | Nov 07, 2012 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2] |
Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00139230 | Oct 05, 2012 | Nov 07, 2012 | View | Grants Info | Organization Applicants |