This grant aims to fund program projects that study the genetic and biological basis of congenital human malformations. Projects should integrate basic, translational, and clinical research focusing on a specific developmental defect. Applicants must propose three component research projects and cores that align with a common central theme. At least one project should use an animal model, and another must be clinical or translational. The research must investigate genes, processes, mechanisms, pathways, or phenotypes related to developmental defects. Applications utilizing non-mammalian or mammalian models are accepted. Closing date: Nov 18, 2015.
Opportunity ID: 277852
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HD-16-009 |
| Funding Opportunity Title: | Developmental Mechanisms of Human Structural Birth Defects (P01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | 2 |
| Assistance Listings: | 93.865 — Child Health and Human Development Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 15, 2015 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 18, 2015 |
| Current Closing Date for Applications: | Nov 18, 2015 |
| Archive Date: | Dec 19, 2015 |
| Estimated Total Program Funding: | $3,330,000 |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities City or township governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Small businesses Special district governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to support innovative, multidisciplinary, interactive, and synergistic program projects (P01s) that integrate basic, translational, and clinical approaches to understanding the developmental biology and genetic basis of significant congenital human malformations. To contain costs, each program project will consist of only three component research projects and associated cores. At least one project must use basic research in an animal model system and at least one project must be clinical or translational in nature. The component research projects must share a common central theme, focus, or objective on a specific major developmental defect or malformation that is genotypically, mechanistically, biologically, or phenotypically analogous or homologous in both animal models and humans. Any non-mammalian or mammalian animal model may be used, as long as it contributes to the common overall theme or objective of the program project. If the component research projects do not share a common developmental gene, process, mechanism, pathway, or phenotype, the application will be considered nonresponsive to this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HD-16-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00217838 | Oct 18, 2015 | Nov 18, 2015 | View |
Package 1
Mandatory forms
277852 RR_SF424_2_0-2.0.pdf
277852 PHS398_CoverPageSupplement_2_0-2.0.pdf
277852 RR_KeyPersonExpanded_2_0-2.0.pdf
277852 RR_OtherProjectInfo_1_3-1.3.pdf
277852 PerformanceSite_2_0-2.0.pdf
277852 PHS398_ResearchPlan_2_0-2.0.pdf
Optional forms
277852 PHS_Additional_IndirectCosts-1.0.pdf
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