The National Institute on Aging is offering a grant to conduct research on ApoE2 and its variants, aiming to understand how they influence longevity and susceptibility to age-related conditions. The research will focus on exploring potential therapeutic targets to prevent or treat aging-related diseases by mimicking the beneficial effects of the ApoE2 variant. Applications for this grant must be submitted by September 7, 2019.
Opportunity ID: 286172
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-16-371 |
| Funding Opportunity Title: | Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 15, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2019 |
| Current Closing Date for Applications: | Sep 07, 2019 |
| Archive Date: | Oct 08, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education Native American tribal governments (Federally recognized) County governments City or township governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this FOA is to support exploratory and developmental new research activities on ApoE2 and other variants to improve understanding of physiologic and cellular differences attributable to the ApoE e2 allele (vs. other ApoE alleles), and how they mediate ApoE e2s differential effects on longevity and risk for age-related conditions. This will aid in the identification of potential therapeutic targets for interventions that prevent or ameliorate aging-related diseases by mimicking favorable differential effects of the ApoE e2 variant, while avoiding adverse effects. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-16-371.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or before January 24, 2018 | PKG00225607 | Sep 16, 2016 | Jan 24, 2018 | View | |
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00236193 | Nov 14, 2017 | Sep 07, 2019 | View |
Package 1
Mandatory forms
286172 RR_SF424_2_0-2.0.pdf
286172 PHS398_CoverPageSupplement_3_0-3.0.pdf
286172 RR_OtherProjectInfo_1_3-1.3.pdf
286172 PerformanceSite_2_0-2.0.pdf
286172 RR_KeyPersonExpanded_2_0-2.0.pdf
286172 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
286172 RR_Budget_1_3-1.3.pdf
286172 RR_SubawardBudget30_1_3-1.3.pdf
286172 PHS398_ModularBudget_1_2-1.2.pdf
286172 PHS_Inclusion_Enrollment_Report-1.0.pdf
286172 PHS_AssignmentRequestForm-1.0.pdf
Package 2
Mandatory forms
286172 RR_SF424_2_0-2.0.pdf
286172 PHS398_CoverPageSupplement_4_0-4.0.pdf
286172 RR_OtherProjectInfo_1_4-1.4.pdf
286172 PerformanceSite_2_0-2.0.pdf
286172 RR_KeyPersonExpanded_2_0-2.0.pdf
286172 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
286172 RR_Budget_1_4-1.4.pdf
286172 RR_SubawardBudget30_1_4-1.4.pdf
286172 PHS398_ModularBudget_1_2-1.2.pdf
286172 PHS_AssignmentRequestForm_2_0-2.0.pdf
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