This department is offering grants to small businesses for developing in vitro screening systems utilizing animal-derived cells to mimic biological interactions and toxicological responses observed in animal tissues. The goal is to create alternative methods to reduce animal testing, improve understanding of toxicity mechanisms, and generate relevant data for chemical exposure assessment.
Opportunity ID: 297097
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-ES-17-008 |
| Funding Opportunity Title: | Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Environment Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 05, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 12, 2018 |
| Current Closing Date for Applications: | Jan 12, 2018 |
| Archive Date: | Feb 17, 2018 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) supports Phase I (R43) and Fast Track (R44) Small Business Innovative Research (SBIR) grant proposals from small businesses concerns (SBCs) to develop novel, physiologically-relevant in vitro screening systems (e.g., engineered 3-dimensional or organotypic models) using cells derived from animal species typically utilized for toxicological testing, which will replicate biological interactions and toxicological responses observed in animal tissues or organs, will produce assay data suitable for comparisons between in vitro and in vivo animal toxicology studies, and may ultimately provide alternative methods to reduce the use of animals in toxicity testing. These systems will provide the improved understanding of biological processes and mechanisms of toxicity, and produce relevant data for alternative chemical exposure assessment methods to reduce animal testing. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-17-008.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00234586 | Dec 12, 2017 | Jan 12, 2018 | View |
Package 1
Mandatory forms
297097 RR_SF424_2_0-2.0.pdf
297097 PHS398_CoverPageSupplement_3_0-3.0.pdf
297097 RR_OtherProjectInfo_1_3-1.3.pdf
297097 PerformanceSite_2_0-2.0.pdf
297097 RR_KeyPersonExpanded_2_0-2.0.pdf
297097 RR_Budget_1_3-1.3.pdf
297097 PHS398_ResearchPlan_3_0-3.0.pdf
297097 SBIR_STTR_Information_1_1-1.1.pdf
Optional forms
297097 RR_SubawardBudget30_1_3-1.3.pdf
297097 PHS_Inclusion_Enrollment_Report-1.0.pdf
297097 PHS_AssignmentRequestForm-1.0.pdf
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