This grant from the National Institute of Dental and Craniofacial Research aims to support innovative research projects targeting residual oral reservoirs for HIV and opportunistic pathogens. The focus is on understanding the mechanisms necessary to eliminate these pathogens post Highly Active Anti-Retroviral Therapy (HAART) treatment. Researchers are encouraged to explore methods for purging these pathogens or developing alternative strategies to eradicate latently infected cells housing HAART-resistant HIV and opportunistic pathogens in oral reservoirs. Application deadline is on July 28, 2015.
Opportunity ID: 263328
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DE-15-003 |
| Funding Opportunity Title: | Approaches to Eliminate HIV and Opportunistic Pathogens from Oral Reservoirs (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 27, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jul 28, 2015 |
| Current Closing Date for Applications: | Jul 28, 2015 |
| Archive Date: | Aug 28, 2015 |
| Estimated Total Program Funding: | $3,500,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments State governments Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Small businesses County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to support novel basic and translational research projects that focus on the biology of residual oral reservoirs for HIV and opportunistic oral pathogens.These studies will advance our understanding of the immunologic, pathogenic, molecular and cellular mechanisms important for eliminating latently persistent, reactivation competent HIV and other opportunistic pathogens from residual oral reservoirs.Specifically, this FOA encourages studies on: 1) purging and abolishing these pathogens after using Highly Active Anti-Retroviral Therapy (HAART) to induce cytopathic killing and immunoclearance; or 2) developing alternative strategies that directly eliminate latently infected cells in which HAART resistant HIV and opportunistic pathogens persist in oral reservoirs. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DE-15-003.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00204483 | Oct 21, 2014 | Jul 28, 2015 | View |
Package 1
Mandatory forms
263328 RR_SF424_2_0-2.0.pdf
263328 PHS398_ResearchPlan_2_0-2.0.pdf
263328 PHS398_CoverPageSupplement_2_0-2.0.pdf
263328 RR_KeyPersonExpanded_2_0-2.0.pdf
263328 RR_OtherProjectInfo_1_3-1.3.pdf
263328 PerformanceSite_2_0-2.0.pdf
Optional forms
263328 RR_SubawardBudget30_1_3-1.3.pdf
263328 PlannedReport-1.0.pdf
263328 PHS398_CumulativeInclusionReport-1.0.pdf
263328 PHS398_ModularBudget_1_2-1.2.pdf
263328 RR_Budget_1_3-1.3.pdf
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