This grant is offered by the National Institute of Allergy and Infectious Diseases for institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program. The aim is to develop preclinical porcine-to-nonhuman primate models for xenotransplantation of various organs. Objectives include understanding rejection mechanisms, improving graft survival, and addressing physiological compatibility. The ultimate goal is to advance xenotransplantation for potential clinical applications. Closing date for applications is September 16, 2019.
Opportunity ID: 316544
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-19-042 |
| Funding Opportunity Title: | Immunobiology of Xenotransplantation (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 30, 2019 |
| Last Updated Date: | May 30, 2019 |
| Original Closing Date for Applications: | Sep 16, 2019 |
| Current Closing Date for Applications: | Sep 16, 2019 |
| Archive Date: | Oct 22, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts State governments City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Private institutions of higher education Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Special district governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications from institutions to participate in the Immunobiology of Xenotransplantation Cooperative Research Program (IXCRP), for the development of preclinical porcine-to-nonhuman primate (NHP) models of pancreatic islet, kidney, heart, lung, or liver xenotransplantation. The goals of this program are to: (1) delineate the cellular and molecular mechanisms of xenograft rejection and/or the induction of immune tolerance; (2) develop effective strategies to improve xenograft survival; and (3) characterize and address the physiological compatibility/limitations of xenografts. The long-term goal of this program is to develop strategies for application of xenotransplantation in the clinic. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-19-042.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00251488 | Aug 16, 2019 | Sep 16, 2019 | View |
Package 1
Mandatory forms
316544 RR_SF424_2_0-2.0.pdf
316544 PHS398_CoverPageSupplement_4_0-4.0.pdf
316544 RR_OtherProjectInfo_1_4-1.4.pdf
316544 PerformanceSite_2_0-2.0.pdf
316544 RR_KeyPersonExpanded_2_0-2.0.pdf
316544 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
316544 RR_Budget_1_4-1.4.pdf
316544 RR_SubawardBudget30_1_4-1.4.pdf
316544 PHS398_ModularBudget_1_2-1.2.pdf
316544 PHS_AssignmentRequestForm_2_0-2.0.pdf
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