The Department of Health is offering a grant to support the continuation of the Epidemiology of Diabetes Interventions and Complications (EDIC) study through a collaborative agreement. This grant aims to follow the EDIC cohort to study the long-term effects of diabetes interventions and complications. The EDIC Clinical Research Center will manage EDIC Clinical Centers to collect data on the development of complications in a well-characterized type 1 diabetes population. This grant focuses on studying various complications such as cardiovascular disease, mortality, severe microvascular disease, neurocognitive impairments, and physical fragility. The EDIC Biostatistics Research Center will also receive support through this grant.
Opportunity ID: 286801
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-16-508 |
| Funding Opportunity Title: | Limited Competition for the Continuation of Epidemiology of Diabetes Interventions and Complications (EDIC) Study Clinical Research Center (Collaborative U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 01, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 08, 2016 |
| Current Closing Date for Applications: | Nov 08, 2016 |
| Archive Date: | Dec 09, 2016 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $3,500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; See FOA for eligibility details. Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to continue to follow the Epidemiology of Diabetes Interventions and Complications (EDIC) cohort through a collaborative cooperative agreement. EDIC is an observational study that was launched at the completion of the Diabetes Control and Complications Trial (DCCT) trial. The DCCT showed that intensive therapy significantly reduced the risk of diabetes complications compared to conventional therapy. At DCCT completion, all cohort members were taught intensive diabetes therapy. In 1994, EDIC was launched to: (1) evaluate the long-term effects of DCCT intensive therapy, (2) describe the long-term effects of glycemia and other risk factors on diabetes complications, and (3) characterize type 1 diabetes complications by supporting collaborative research to utilize the EDIC cohort as well as its data set and biologic/genetic samples. To date, EDIC has: (1) demonstrated a continued benefit of intensive therapy on the development and progression of diabetes complications, and (2) characterized the development and progression of diabetes complications. The primary purpose of this FOA is to support the EDIC Clinical Research Center to continue follow-up of the EDIC cohort to study the development of complications and the longer term course of type 1 diabetes in a well characterized type 1 diabetes population, including but not limited to cardiovascular disease, mortality, severe microvascular disease (blindness, kidney failure, amputation), neurocognitive impairments, and physical fragility. The EDIC Clinical Research Center will manage and support EDIC Clinical Centers, which are responsible for the conduct of all EDIC core activities as described in the protocol and Manual of Operations and as required by the local Institutional Review Board. The EDIC Clinical Research Center will also facilitate the conduct of all approved EDIC ancillary studies. The Clinical Centers will collect data in accordance with established study procedures and will submit all data and samples to the Biostatistics Research Center and central laboratory and other core facilities as appropriate and as required by the protocol(s). RFA DK-16-509 will support continuation of the EDIC Biostatistics Research Center. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-16-508.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00226274 | Oct 08, 2016 | Nov 08, 2016 | View |
Package 1
Mandatory forms
286801 RR_SF424_2_0-2.0.pdf
286801 PHS398_CoverPageSupplement_3_0-3.0.pdf
286801 RR_OtherProjectInfo_1_3-1.3.pdf
286801 PerformanceSite_2_0-2.0.pdf
286801 RR_KeyPersonExpanded_2_0-2.0.pdf
286801 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
286801 RR_Budget_1_3-1.3.pdf
286801 RR_SubawardBudget30_1_3-1.3.pdf
286801 PHS398_ModularBudget_1_2-1.2.pdf
286801 PHS_Inclusion_Enrollment_Report-1.0.pdf
286801 PHS_AssignmentRequestForm-1.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
