National Institute of Environmental Health Sciences Grant: Investigating Environmental Chemical Exposures in Obesity and Metabolic Syndrome Development (R21)

This grant opportunity aims to support research on the connection between environmental chemical exposures and the development of obesity, type 2 diabetes, and metabolic syndrome. The National Institute of Environmental Health Sciences seeks proposals that investigate how various environmental exposures contribute to weight gain, insulin sensitivity, glucose tolerance, and lipid metabolism in animal models or human studies. Emphasis is placed on exposures during crucial developmental periods, such as in utero or early childhood, and linking them to early disease biomarkers. Researchers are expected to identify new environmental chemicals potentially influencing obesity and metabolic syndrome markers.

Opportunity ID: 170174

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PA-12-184
Funding Opportunity Title::	Role of Environmental Chemical Exposures in the Development of Obesity, Type 2 Diabetes and Metabolic Syndrome (R21)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Environment
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.113 — Environmental Health
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	May 11, 2012
Last Updated Date::
Original Closing Date for Applications::	Sep 07, 2015
Current Closing Date for Applications::	Sep 07, 2015
Archive Date::	Oct 08, 2015
Estimated Total Program Funding::
Award Ceiling::	$200,000
Award Floor::	$

Eligibility

Eligible Applicants::

State governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This Funding Opportunity Announcement (FOA), issued by the National Institute of Environmental Health Sciences (NIEHS), encourages grant applications to understand the role of environmental chemical exposures in the development of obesity, type 2 diabetes and/or metabolic syndrome. Applications must link an environmental exposure to the increased incidence of weight gain, type 2 diabetes and aspects of metabolic syndrome in animal models or human studies. While any exposure window is acceptable it is anticipated that the most sensitive time for exposures to affect the disease outcomes will be during development e.g., in utero and/or neonatal or early childhood. For human studies developmental exposures (in utero and early childhood) should be linked to early biomarkers of disease onset. Animal studies should focus on identifying new environmental chemicals that alter weight gain, insulin sensitivity and glucose tolerance and altered lipid metabolism indicative of obesity, type 2 diabetes and/or metabolic syndrome.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00121310
Opening Date:	Sep 16, 2012
Closing Date:	Sep 24, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]