Opportunity ID: 265488

General Information

Document Type: Grants Notice
Funding Opportunity Number: RFA-AG-15-013
Funding Opportunity Title: Analyses of Datasets on Older Populations with High Prevalence of Mobility Disability to Develop Clinically Meaningful Diagnostic Cut-Points for Low Muscle Mass and/or Low Muscle Strength (U01)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Cooperative Agreement
Category of Funding Activity: Health
Category Explanation:
Expected Number of Awards: 1
Assistance Listings: 93.866 — Aging Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Sep 16, 2014
Last Updated Date:
Original Closing Date for Applications: Jan 15, 2015
Current Closing Date for Applications: Jan 15, 2015
Archive Date: Feb 15, 2015
Estimated Total Program Funding: $750,000
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Private institutions of higher education
Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Independent school districts
Native American tribal organizations (other than Federally recognized tribal governments)
For profit organizations other than small businesses
Public and State controlled institutions of higher education
City or township governments
Special district governments
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Others (see text field entitled “Additional Information on Eligibility” for clarification)
State governments
County governments
Native American tribal governments (Federally recognized)
Additional Information on Eligibility: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name: National Institutes of Health
Description: This initiative invites applications for support of analyses of existing data (or data whose collection will be completed by one year from the date of this FOA) from older populations with high prevalence of mobility disability, low muscle mass, and low muscle strength (weakness). Interventions targeted at low muscle mass and/or weakness may prevent or reduce mobility disability in some older persons. To assess the efficacy of such interventions against mobility disability, there is a need to test them in persons in whom muscle mass and/or strength are (or will be) sufficiently low to be likely contributors to disability. Thus there is a need for evidence-based diagnostic cut-points to define target populations for treatments.

Applications submitted in response to this FOA should support development and evaluation of diagnostic cut-points based on analyses of relations of mobility disability to muscle mass and strength. These analyses should extend and expand upon analyses to date on this topic, which have identified and proposed cut-points for low muscle mass and weakness. Studies supported through this FOA should clarify relations between muscle mass and strength, impaired physical function, and mobility disability, and their implications for setting diagnostic cut-points, through analyses of data from populations with substantially more individuals with mobility disability than were included in previous analyses.

Applicants are encouraged to consider combining datasets from multiple populations that contain information on all of the following: at least one objective measure of muscle mass at the same anatomic site(s) common to all included studies, at least one direct measure of muscle strength common to included data sets, gait speed, and self-reported mobility status in populations of older adults. Analyses of relations to other measures of strength, muscle power, and physical performance (e.g., Short Physical Performance Battery), and mobility disability are encouraged.

Link to Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-15-013.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email:FBOWebmaster@OD.NIH.GOV

Version History

Version Modification Description Updated Date

Related Documents

Packages

Agency Contact Information: NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV

Email: FBOWebmaster@OD.NIH.GOV

Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-C FORMS-C PKG00206043 Dec 15, 2014 Jan 15, 2015 View

Package 1

Mandatory forms

265488 RR_SF424_2_0-2.0.pdf

265488 PHS398_ResearchPlan_2_0-2.0.pdf

265488 PHS398_CoverPageSupplement_2_0-2.0.pdf

265488 RR_KeyPersonExpanded_2_0-2.0.pdf

265488 RR_OtherProjectInfo_1_3-1.3.pdf

265488 PerformanceSite_2_0-2.0.pdf

Optional forms

265488 RR_SubawardBudget30_1_3-1.3.pdf

265488 PlannedReport-1.0.pdf

265488 PHS398_CumulativeInclusionReport-1.0.pdf

265488 PHS398_ModularBudget_1_2-1.2.pdf

265488 RR_Budget_1_3-1.3.pdf

2025-07-09T18:06:21-05:00

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