NIDDK is offering a grant for the Kidney Precision Medicine Project Tissue Interrogation Sites (UG3/UH3) to advance the analysis of human kidney tissue. The grant aims to create a kidney tissue atlas, define disease subgroups, and identify potential therapies for acute kidney injury and chronic kidney disease. The grant includes an exploratory UG3 phase to demonstrate tissue interrogation capabilities and a UH3 phase for validation and technology development. Applicants must have experience with advanced technologies for analyzing kidney tissue. The grant is focused on human studies and does not support research involving animal or model systems. Application deadline is December 6, 2016.
Opportunity ID: 287582
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-16-027 |
| Funding Opportunity Title: | Kidney Precision Medicine Project Tissue Interrogation Sites (UG3/UH3) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 17, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 06, 2016 |
| Current Closing Date for Applications: | Dec 06, 2016 |
| Archive Date: | Jan 06, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses City or township governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Independent school districts Private institutions of higher education Public and State controlled institutions of higher education State governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) requests applications for the Kidney Precision Medicine Project (KPMP) Tissue Interrogation Sites (TIS) to use and develop innovative technologies to analyze human kidney tissue. The TIS will collaborate with the KPMP Recruitment Sites and Central Hub to obtain and evaluate kidney biopsies from participants with acute kidney injury and chronic kidney disease, create a kidney tissue atlas, define disease subgroups, and identify critical cells, pathways and targets for novel therapies. Applicant teams should have documented experience with a current state-of-the-art method that can be used or adapted to interrogate human kidney tissue. The initial UG3 exploratory phase will be used to demonstrate that the site can interrogate existing tissue samples and small numbers of new biopsies. The UG3 phase will also encourage the development of next generation tissue interrogation technologies that probe the structural, functional and molecular complexities of kidney tissue. UG3 projects that have met their milestones will be administratively considered by the NIDDK and prioritized for transition to the UH3 implementation phase. UH3 awards will support further validation, scale-up and technology development. Applicants must address both the UG3 and UH3 phases. This FOA is intended to support only human studies and applications that include animal or model systems are not responsive. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-16-027.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00226950 | Nov 06, 2016 | Dec 06, 2016 | View |
Package 1
Mandatory forms
287582 RR_SF424_2_0-2.0.pdf
287582 PHS398_CoverPageSupplement_3_0-3.0.pdf
287582 RR_OtherProjectInfo_1_3-1.3.pdf
287582 PerformanceSite_2_0-2.0.pdf
287582 RR_KeyPersonExpanded_2_0-2.0.pdf
287582 RR_Budget_1_3-1.3.pdf
287582 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
287582 RR_SubawardBudget30_1_3-1.3.pdf
287582 PHS_Inclusion_Enrollment_Report-1.0.pdf
287582 PHS_AssignmentRequestForm-1.0.pdf
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