The NIDDK Inflammatory Bowel Disease Genetics Consortium aims to identify genes predisposing to IBD and elucidate their mechanisms. This grant seeks to renew the IBDGC, focusing on identifying risk-conferring genes and understanding how they affect IBD pathophysiology. The Data Coordinating Center will manage collaboration among Genetic Research Centers, sample collection, data submission, and analysis. It will also facilitate pilot projects for rapid follow-up on discoveries, coordinate with international partners and external investigators, and ensure the smooth operation of various committees within the consortium. Applicants must adhere to the operational decisions of the Steering Committee. Closing date for applications is Dec 14, 2016.
Opportunity ID: 287585
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-16-510 |
| Funding Opportunity Title: | Limited Competition for Data Coordinating Center (DCC) for NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) (U24) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 17, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 14, 2016 |
| Current Closing Date for Applications: | Dec 14, 2016 |
| Archive Date: | Jan 14, 2017 |
| Estimated Total Program Funding: | $1,476,000 |
| Award Ceiling: | $1,062,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Independent school districts Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Special district governments Public housing authorities/Indian housing authorities Small businesses State governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) was established in July, 2002 for the purpose of identifying genes predisposing to IBD. Since its establishment, the IBDGC, in collaboration with the International IBD Genetics Consortium, has identified about 200 such susceptibility loci. However, most of these loci include multiple genes, and for the great majority of the loci, specific casual genes and alleles have not yet been identified. The mechanisms by which the most of the causative genes influence IBD pathophysiology also remain unknown. The purpose of this FOA is to renew the IBDGC to identify risk-conferring and protective variants of causal genes for IBD, and to elucidate the mechanisms by which these variants influence the pathophysiology of IBD. The DCC will coordinate collaboration among the Genetic Research Centers (GRCs, described in the companion FOA RFA-DK-16-029), enrollment of subjects into the study, submission of blood and other biological samples to centralized repositories, processing of blood samples for extraction of DNA and isolation of cells and serum, submission of clinical, genetic, and molecular data to central databases, and analyses of data, and manage the operations of the Steering Committee and other operational committees. The DCC will also coordinate the development of pilot projects for rapid follow-up of emerging findings by members of the IBDGC and external collaborators. In addition, the DCC will coordinate the collaboration of the IBDGC with the International IBDGC, and with other external investigators conducting ancillary studies. The PD/PI of the DCC shall serve as a voting member of the Steering Committee of the IBDGC, and be bound by all of the operational decisions of this Committee. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-16-510.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00226973 | Nov 14, 2016 | Dec 14, 2016 | View |
Package 1
Mandatory forms
287585 RR_SF424_2_0-2.0.pdf
287585 PHS398_CoverPageSupplement_3_0-3.0.pdf
287585 RR_OtherProjectInfo_1_3-1.3.pdf
287585 PerformanceSite_2_0-2.0.pdf
287585 RR_KeyPersonExpanded_2_0-2.0.pdf
287585 RR_Budget_1_3-1.3.pdf
287585 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
287585 RR_SubawardBudget30_1_3-1.3.pdf
287585 PHS_Inclusion_Enrollment_Report-1.0.pdf
287585 PHS_AssignmentRequestForm-1.0.pdf
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