The National Institute on Aging offers a grant for research using non-mammalian laboratory animals to explore the underlying causes of neurodegeneration. This grant aims to provide new insights into molecular networks relevant to Alzheimer’s disease and related dementias. Utilizing systems biology approaches, researchers can uncover interactions and regulatory networks contributing to neurodegeneration. The focus is on discovering mechanisms without the need for genetically modified mammals typically used in Alzheimer’s research. Studies involving humans or mammals are not supported. Application deadline: Feb 21, 2018.
Opportunity ID: 298429
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-18-021 |
| Funding Opportunity Title: | Systems Biology Approaches using Non-Mammalian Laboratory Animals to Uncover Causes of Neurodegeneration that Might Underlie Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 06, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Feb 21, 2018 |
| Current Closing Date for Applications: | Feb 21, 2018 |
| Archive Date: | Mar 29, 2018 |
| Estimated Total Program Funding: | $3,300,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Independent school districts For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Public housing authorities/Indian housing authorities City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education State governments Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Institute on Aging is seeking applications on systems biology approaches using non-mammalian laboratory animal models to increase our understanding of the basic biology underpinning neurodegeneration. It is expected that research supported under this FOA will provide new insights into molecular networks that might be involved in causing, amplifying or protecting against neurodegeneration, and that, in turn, might ultimately contribute to Alzheimer’s disease or related dementias. Importantly, a major goal of this FOA is to use interaction and regulatory networks produced and analyzed using systems biology to gain these new insights. Because this FOA is directed toward discovery, currently employed genetically modified laboratory animals used to study AD are not required, although they may be used. Because this FOA requires systems biology approaches, data used to build interaction or regulatory networks may also come from humans or other mammals in which AD, related dementias, or aging-related cognitive decline have been observed. This FOA will only support studies using non-mammalian laboratory animal models; studies involving humans or experiments with mammals will not be allowed under this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-18-021.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00236306 | Jan 21, 2018 | Feb 21, 2018 | View | |
| FORMS-D | FORMS-D package posted in error – you must use the FORMS-E package for this opportunity. | PKG00235828 | Nov 16, 2017 | Nov 17, 2017 | View |
Package 1
Mandatory forms
298429 RR_SF424_2_0-2.0.pdf
298429 PHS398_CoverPageSupplement_4_0-4.0.pdf
298429 RR_OtherProjectInfo_1_4-1.4.pdf
298429 PerformanceSite_2_0-2.0.pdf
298429 RR_KeyPersonExpanded_2_0-2.0.pdf
298429 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
298429 RR_Budget_1_4-1.4.pdf
298429 RR_SubawardBudget30_1_4-1.4.pdf
298429 PHS398_ModularBudget_1_2-1.2.pdf
298429 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
298429 RR_SF424_2_0-2.0.pdf
298429 PHS398_CoverPageSupplement_3_0-3.0.pdf
298429 RR_OtherProjectInfo_1_3-1.3.pdf
298429 PerformanceSite_2_0-2.0.pdf
298429 RR_KeyPersonExpanded_2_0-2.0.pdf
298429 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
298429 RR_Budget_1_3-1.3.pdf
298429 RR_SubawardBudget30_1_3-1.3.pdf
298429 PHS398_ModularBudget_1_2-1.2.pdf
298429 PHS_Inclusion_Enrollment_Report-1.0.pdf
298429 PHS_AssignmentRequestForm-1.0.pdf
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