NINDS is offering the Stroke Preclinical Assessment Network (SPAN) Grant to accelerate the identification of promising neuroprotective therapies for acute stroke. The network will support late-stage preclinical testing of neuroprotectants, aiming to improve outcomes and extend the therapeutic window for reperfusion. This grant focuses on bridging the gap between preclinical and clinical studies in a cost-effective manner using adaptive design. The deadline for applications is December 13, 2018.
Opportunity ID: 307997
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-18-033 |
| Funding Opportunity Title: | Stroke Preclinical Assessment Network (SPAN) to Support Translational Studies for Acute Neuroprotection (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 06, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 13, 2018 |
| Current Closing Date for Applications: | Dec 13, 2018 |
| Archive Date: | Jan 18, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts State governments Public housing authorities/Indian housing authorities Small businesses Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments Private institutions of higher education Native American tribal governments (Federally recognized) Special district governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this initiative is to accelerate the identification of the most promising neuroprotective therapies, and span the gap between preclinical and clinical testing, by creating a preclinical stroke network to support late stage preclinical parallel testing of promising neuroprotectants to be given prior to or at the time of reperfusion, with clinically relevant long-term outcomes and comorbidities. This approach will help to determine if an intervention can indeed improve outcome as compared to reperfusion alone and/or extend the therapeutic window for reperfusion, in an experimental controlled setting and in a time and cost-effective manner using an adaptive design approach. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-18-033.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00244263 | Nov 13, 2018 | Dec 13, 2018 | View |
Package 1
Mandatory forms
307997 RR_SF424_2_0-2.0.pdf
307997 PHS398_CoverPageSupplement_4_0-4.0.pdf
307997 RR_OtherProjectInfo_1_4-1.4.pdf
307997 PerformanceSite_2_0-2.0.pdf
307997 RR_KeyPersonExpanded_2_0-2.0.pdf
307997 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
307997 RR_Budget_1_4-1.4.pdf
307997 RR_SubawardBudget30_1_4-1.4.pdf
307997 PHS398_ModularBudget_1_2-1.2.pdf
307997 PHS_AssignmentRequestForm_2_0-2.0.pdf