This grant opportunity from the National Institutes of Health focuses on investigating the neuropathophysiology of HIV-associated neurological disorders using induced microglia and cerebral organoids from patient iPSC lines. Research is aimed at understanding these disorders in the context of long-term antiretroviral therapy conditions. Applications to explore the cellular and molecular mechanisms of HAND are welcome, with a deadline of November 12, 2019.
Opportunity ID: 318265
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-20-023 |
| Funding Opportunity Title: | Modeling HIV Neuropathology Using Microglia from Human iPSC and Cerebral Organoids (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 10, 2019 |
| Last Updated Date: | Jul 10, 2019 |
| Original Closing Date for Applications: | Nov 12, 2019 |
| Current Closing Date for Applications: | Nov 12, 2019 |
| Archive Date: | Dec 18, 2019 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) State governments Small businesses County governments Native American tribal governments (Federally recognized) Private institutions of higher education For profit organizations other than small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Special district governments Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites research grant applications to study the cellular and molecular mechanisms delineating the neuropathophysiology of HIV-associated neurological disorders (HAND) in the setting of long-term combination antiretroviral therapy (cART) conditions using induced microglia and cerebral organoids generated from patient derived induced pluripotent stem cell (iPSC) lines. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-20-023.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00252835 | Oct 12, 2019 | Nov 12, 2019 | View |
Package 1
Mandatory forms
318265 RR_SF424_2_0-2.0.pdf
318265 PHS398_CoverPageSupplement_4_0-4.0.pdf
318265 RR_OtherProjectInfo_1_4-1.4.pdf
318265 PerformanceSite_2_0-2.0.pdf
318265 RR_KeyPersonExpanded_2_0-2.0.pdf
318265 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
318265 RR_Budget_1_4-1.4.pdf
318265 RR_SubawardBudget30_1_4-1.4.pdf
318265 PHS398_ModularBudget_1_2-1.2.pdf
318265 PHS_AssignmentRequestForm_2_0-2.0.pdf
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