NHGRI is offering the Centers for Mendelian Genomics Program grant to discover as many causal genes for human Mendelian diseases and traits as possible, enhance discovery strategies, share resources, and promote collaborations worldwide. The grant aims to improve sample solicitation, study designs, data analysis, and efficiency of discovery pipelines. By disseminating tools and methods, NHGRI intends to lead the field towards understanding the necessary methods, scale, and infrastructure for uncovering most causal genes for human Mendelian conditions. Applications are sought to contribute to cutting-edge research in genetics before the closing date on Apr 07, 2015.
Opportunity ID: 270448
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-15-002 |
| Funding Opportunity Title: | Centers for Mendelian Genomics (UM1) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 12, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 07, 2015 |
| Current Closing Date for Applications: | Apr 07, 2015 |
| Archive Date: | May 08, 2015 |
| Estimated Total Program Funding: | $40,000,000 |
| Award Ceiling: | $5,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Private institutions of higher education City or township governments Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Small businesses Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites applications for the Centers for Mendelian Genomics Program (CMG Program). With this reissuance, NHGRI intends to achieve the following specific objectives. First, the Program will aim to discover as many genes that bear causal genetic variants (“causal genes”) for human Mendelian diseases and non-disease Mendelian traits (“Mendelian conditions”) as possible, using genome-wide sequencing and other complementary genomic approaches at the funded centers, and through collaborations with clinical and genetic researchers worldwide. Second, the Program will aim to enhance the chances of success in causal gene discoveries by improving sample solicitation strategies, discovery approaches, study designs, data analysis methods, and costs and efficiency of the discovery pipelines. Third, the Program will aim to enable others to discover more causal genes by disseminating the methods, tools, and other resources that will be developed under this FOA. Finally, the Program will facilitate common interests-based collaborations and avoid unproductive duplication of efforts on causal gene discoveries, through worldwide coordination. At a higher level, NHGRI intends that these activities will lead to insights on what methods, scale, and infrastructure will be necessary to discover all or most of the causal genes for human Mendelian conditions, and bring the field forward toward this goal. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-15-002.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00210706 | Mar 07, 2015 | Apr 07, 2015 | View |
Package 1
Mandatory forms
270448 RR_SF424_2_0-2.0.pdf
270448 PHS398_ResearchPlan_2_0-2.0.pdf
270448 PHS398_CoverPageSupplement_2_0-2.0.pdf
270448 RR_Budget_1_3-1.3.pdf
270448 RR_KeyPersonExpanded_2_0-2.0.pdf
270448 RR_OtherProjectInfo_1_3-1.3.pdf
270448 PerformanceSite_2_0-2.0.pdf
Optional forms
270448 PlannedReport-1.0.pdf
270448 PHS398_CumulativeInclusionReport-1.0.pdf
270448 RR_SubawardBudget30_1_3-1.3.pdf
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