The National Institute of General Medical Sciences (NIGMS) offers this Collaborative Program Grant for Multidisciplinary Teams (RM1) to fund highly integrated research teams of three to six Principal Investigators. This grant aims to address ambitious, challenging research questions vital to the NIGMS mission, particularly those requiring considerable synergy and managed team interactions beyond individual efforts. Teams are encouraged to pursue far-reaching objectives for major field advancements. This funding opportunity now allows NIH-defined clinical trials, but strictly excludes Phase I, II, or III trials focused on safety, efficacy, or regulatory approval. Projects for resource creation, new technologies, or infrastructure development are not appropriate. The closing date for this opportunity is Jan 27, 2026.
Opportunity ID: 345794
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-077 |
| Funding Opportunity Title: | Collaborative Program Grant for Multidisciplinary Teams (RM1 – Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 03, 2023 |
| Last Updated Date: | Feb 03, 2023 |
| Original Closing Date for Applications: | Jan 27, 2026 |
| Current Closing Date for Applications: | Jan 27, 2026 |
| Archive Date: | Mar 04, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Private institutions of higher education County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Special district governments City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This funding opportunity announcement (FOA) is designed to support highly integrated research teams of three to six PD/PIs to address ambitious and challenging research questions that are important for the mission of NIGMS and are beyond the scope of one or two investigators. Collaborative program teams are expected to accomplish goals that require considerable synergy and managed team interactions. Project goals should not be achievable with a collection of individual efforts or projects. Teams are encouraged to consider far-reaching objectives that will produce major advances in their fields.Applications that are mainly focused on the creation, expansion, and/or maintenance of community resources, creation of new technologies or infrastructure development are not appropriate for this FOA.This FOA is being reissued to allow submission of applications that include NIH defined clinical trials. NIGMS will not accept clinical trials that are designed to test safety and efficacy of interventions (Phase I, Phase II, Phase III) for the purpose of future clinical treatment and/or regulatory approval in response to this FOA. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-077.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 345794 Full Announcement-PAR-23-077 -> PAR-23-077-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00279665 | Apr 26, 2023 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289071 | Nov 26, 2024 | Jan 27, 2026 | View |
Package 1
Mandatory forms
345794 RR_SF424_5_0-5.0.pdf
345794 PHS398_CoverPageSupplement_5_0-5.0.pdf
345794 RR_OtherProjectInfo_1_4-1.4.pdf
345794 PerformanceSite_4_0-4.0.pdf
345794 RR_KeyPersonExpanded_4_0-4.0.pdf
345794 RR_Budget_3_0-3.0.pdf
345794 PHS398_ResearchPlan_5_0-5.0.pdf
345794 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345794 RR_SubawardBudget30_3_0-3.0.pdf
345794 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
345794 RR_SF424_5_0-5.0.pdf
345794 PHS398_CoverPageSupplement_5_0-5.0.pdf
345794 RR_OtherProjectInfo_1_4-1.4.pdf
345794 PerformanceSite_4_0-4.0.pdf
345794 RR_KeyPersonExpanded_4_0-4.0.pdf
345794 RR_Budget_3_0-3.0.pdf
345794 PHS398_ResearchPlan_5_0-5.0.pdf
345794 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345794 RR_SubawardBudget30_3_0-3.0.pdf
345794 PHS_AssignmentRequestForm_3_0-3.0.pdf
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