This grant, offered by the Rare and Atypical Diabetes NeTwork (RADIANT), invites applications from its two previously funded research centers. The purpose is to continue the comprehensive study of rare and atypical diabetes mellitus. Awardees will further identify and analyze phenotypic and genotypic defects, aiming to provide crucial insights into more common, heterogeneous forms of diabetes. RADIANT will also expand its role in developing vital community resources, facilitating research through the systematic collection and dissemination of valuable data and samples. A key focus for this grant cycle includes establishing precision diagnoses for new Mendelian diabetes forms by enrolling family members to identify potential causal variants. Additionally, in vitro and basic studies utilizing induced pluripotent stem cells (iPSCs) will establish variant pathogenicity.
Opportunity ID: 345848
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-22-511 |
| Funding Opportunity Title: | Limited Competition for the Continuation of the Rare and Atypical Diabetes NeTwork (RADIANT) Specialized Study Centers (U54 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 07, 2023 |
| Last Updated Date: | Feb 07, 2023 |
| Original Closing Date for Applications: | Jun 07, 2023 |
| Current Closing Date for Applications: | Jun 07, 2023 |
| Archive Date: | Jul 13, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications from the two previously funded Rare and Atypical DIAbetes NeTwork (RADIANT) research centers to further study rare and atypical forms of diabetes mellitus. These centers will continue to identify and analyze phenotypic and genotypic defects that may provide insights into more common, heterogeneous forms of diabetes mellitus in the general population. RADIANT will also continue to develop community resources to advance research in this area through the collection and dissemination of data and samples for access by the broad research community. During this grant cycle, RADIANT will establish precision diagnoses for new Mendelian forms of diabetes by enrolling family members of previously enrolled participants with a family history suggestive of a Mendelian form of diabetes to aid in identifying potential causal variants. In addition, in vitro and basic studies leveraging induced pleuripotent stem cells (iPSCs) differentiated into tissues of interest will be used to establish pathogenicity of potential causal variants. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-22-511.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 345848 Full Announcement-RFA-DK-22-511 -> RFA-DK-22-511-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00279723 | May 07, 2023 | Jun 07, 2023 | View |
Package 1
Mandatory forms
345848 RR_SF424_5_0-5.0.pdf
345848 PHS398_CoverPageSupplement_5_0-5.0.pdf
345848 RR_OtherProjectInfo_1_4-1.4.pdf
345848 PerformanceSite_4_0-4.0.pdf
345848 RR_KeyPersonExpanded_4_0-4.0.pdf
345848 PHS398_ResearchPlan_5_0-5.0.pdf
345848 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345848 PHS_Additional_IndirectCosts_2_0-2.0.pdf
345848 PHS_AssignmentRequestForm_3_0-3.0.pdf
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