The Department of Defense is offering this Breast Cancer Clinical Translational Research (CTR) Award to significantly improve breast cancer prevention and therapy. This grant is for advancing promising research findings into clinical applications for patients or at-risk populations. It supports projects likely to have a major impact, focusing on preventing primary or recurrent breast cancer and developing new treatments to halt progression to metastasis. Applicants must demonstrate proof of concept and efficacy in an in vivo system, with preliminary data supporting the feasibility of advancing novel translational research into a prospective clinical trial. Successful proposals will include a clear experimental and statistical plan, alongside demonstrated access to an appropriate patient population to ensure meaningful clinical outcomes during the award period.
Opportunity ID: 146134
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | W81XWH-12-BCRP-CTR |
| Funding Opportunity Title: | DOD Breast Cancer Clinical Translational Research Award |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | 3 |
| Assistance Listings: | 12.420 — Military Medical Research and Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 23, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Aug 15, 2012 |
| Current Closing Date for Applications: | Aug 15, 2012 |
| Archive Date: | Sep 14, 2012 |
| Estimated Total Program Funding: | $9,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | – |
Additional Information
| Agency Name: | Dept. of the Army — USAMRAA |
| Description: | The BCRP Clinical Translational Research (CTR) Award is intended to promote significant improvements over current approaches to breast cancer prevention and therapy, such as studies that will prevent primary or recurrent breast cancer and studies that may result in a new treatment to prevent breast cancer progression to metastasis. The CTR Award supports research projects that are likely to have a major impact on breast cancer by applying promising research findings to patients with, or populations at risk for, breast cancer. Principal Investigators (PIs) and their collaborators may have originated projects in their laboratories that will form the basis for 1-2 years of advanced translational research leading to a prospective clinical trial to be conducted during this award period. Alternatively, PIs may leverage partnerships with industry. The ability to conduct the required translational research and early phase clinical trial during the award period must be demonstrated. Applications must include preliminary data and a solid rationale to support the feasibility of advancing novel translational research to a prospective clinical trial. Due to the short period for the advanced translational research phase, PIs must have already demonstrated proof of concept and efficacy in an in vivo system at the time of application submission. Applications also must include a clear experimental plan and a properly powered statistical plan to perform the clinical trial. Investigators must demonstrate availability of and access to an appropriate patient population that will support meaningful clinical outcomes. |
| Link to Additional Information: | – |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
CDMRP Help Desk: 301-682-5507; help@cdmrp.org
Email:help@cdmrp.org |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 146134 Full Announcement-1 -> fy12 bcrp ctr pa_gg.pdf
Packages
| Agency Contact Information: | CDMRP Help Desk: 301-682-5507; help@cdmrp.org Email: help@cdmrp.org |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.420 | PKG00099432 | Feb 23, 2012 | Aug 15, 2012 | View |
Package 1
Mandatory forms
146134 RR_SF424_1_2-1.2.pdf
146134 PerformanceSite_1_4-1.4.pdf
146134 RR_Budget-1.1.pdf
Optional forms
146134 RR_SubawardBudget30-1.2.pdf
146134 RR_KeyPersonExpanded_1_2-1.2.pdf
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