The National Human Genome Research Institute (NHGRI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) invite applications for a Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression (dGTEx) Project. This grant is for establishing a central hub to support the dGTEx initiative, which aims to catalog and analyze transcriptional profiles from a wide variety of post-mortem tissues obtained from neonates, children, and adolescents. The selected LDACC will fulfill two primary roles: operating as a molecular laboratory to process tissue samples for sequencing and biobanking, and serving as a data analysis and coordinating center. Responsibilities include ensuring coordination with the Biospecimen Procurement Center, monitoring study progress, performing essential gene expression analyses, and harmonizing datasets for deposit in public repositories.
Opportunity ID: 327792
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-20-039 |
| Funding Opportunity Title: | Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression Project(U24) (Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 19, 2020 |
| Last Updated Date: | Jun 19, 2020 |
| Original Closing Date for Applications: | Nov 13, 2020 |
| Current Closing Date for Applications: | Nov 13, 2020 |
| Archive Date: | Dec 19, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments City or township governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities For profit organizations other than small businesses County governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Human Genome Research Institute (NHGRI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development are coordinating efforts for establishing a Developmental Genotype-Tissue Expression (dGTEx) project, to catalog and analyze transcriptional profiles from a wide variety of tissues obtained from neonates, children, and adolescents in a post-mortem setting. The purpose of this FOA is to solicit applications to develop and implement a Laboratory, Data Analysis, and Coordinating Center (LDACC) for the Developmental Genotype-Tissue Expression (dGTEx) Project. The LDACC will perform 2 major functions: a molecular laboratory, and a data analysis and coordinating center. As a molecular laboratory, the LDACC will work with the Biospecimen Procurement Center (BPC) funded by NICHD to process tissue samples for sequencing and biobanking. Responsibilities as a data analysis and coordinating center include ensuring close coordination with the BPC, monitoring study progress and laboratory performance, performing basic analysis of data for gene expression analyses, and harmonizing and submitting datasets to be deposited in repositories such as the AnVIL ((Analysis, Visualization, and Informatics Lab-space) https://anvilproject.org/) or the GTEx portal (https://gtexportal.org/home/). |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-20-039.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00262243 | Oct 13, 2020 | Nov 13, 2020 | View |
Package 1
Mandatory forms
327792 RR_SF424_2_0-2.0.pdf
327792 PHS398_CoverPageSupplement_5_0-5.0.pdf
327792 RR_OtherProjectInfo_1_4-1.4.pdf
327792 PerformanceSite_2_0-2.0.pdf
327792 RR_KeyPersonExpanded_2_0-2.0.pdf
327792 RR_Budget_1_4-1.4.pdf
327792 PHS398_ResearchPlan_4_0-4.0.pdf
327792 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
327792 RR_SubawardBudget30_1_4-1.4.pdf
327792 PHS_AssignmentRequestForm_3_0-3.0.pdf
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