National Institutes of Health: Advancing Single Cell Analysis with Innovative Tools and Technologies Grant (R21)

The National Institutes of Health is offering a grant to develop cutting-edge tools for identifying cell diversity within tissues. The focus is on enhancing sensitivity, selectivity, and resolution for studying individual cells in complex biological environments. Emphasis is placed on preserving cell viability for repeated observations. Researchers are encouraged to push the boundaries of current technology to better understand cellular states and disease mechanisms. Proposals should include proof-of-concept testing in living organisms, aiming to revolutionize single cell analysis and improve insights into disease biology.

Opportunity ID: 249376

Apply

General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-RM-13-021
Funding Opportunity Title::	Exceptionally Innovative Tools and Technologies for Single Cell Analysis (R21)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.310 — Trans-NIH Research Support
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Dec 18, 2013
Last Updated Date::
Original Closing Date for Applications::	Apr 04, 2014
Current Closing Date for Applications::	Apr 04, 2014
Archive Date::	May 05, 2014
Estimated Total Program Funding::	$ 2,000,000
Award Ceiling::	$200,000
Award Floor::	$

Eligibility

Eligible Applicants::

Public and State controlled institutions of higher education

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed

Additional Information

Agency Name::	National Institutes of Health
Description::	This Funding Opportunity Announcement (FOA) issued by the National Institutes of Health, solicits early stage, high-risk/high-impact applications to develop next-generation tools that distinguish heterogeneous states among cells in situ. Applications should define the current state of technology as a benchmark against which the new tool(s) will be measured and should propose proof-of-concept testing of the tool(s) in a complex biological tissue or living organism. The new tools should provide substantially increased sensitivity, selectivity, spatiotemporal resolution, scalability of multiple global or functional measures of single cells. A particular emphasis for this FOA is on measures that minimize cell perturbation and permit viability of cells for repeated measures over time. These novel technologies will aid in obtaining a fine-grained, integrative and dynamic view of heterogeneous cellular states/classes and will provide innovative platforms to transform research into the cellular basis of diseases.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.310
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00191180
Opening Date:	Mar 04, 2014
Closing Date:	Apr 04, 2014
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3]