NIH: BRAIN Initiative for Cell-Type Classification in the Brain (U01)

The NIH is offering a grant as part of the BRAIN Initiative to develop innovative strategies for categorizing cell types in the brain. Projects should aim to create a comprehensive inventory of cell types by integrating molecular identity with connectivity, morphology, and location. The grant supports pilot projects that utilize statistical methods to establish a taxonomy of cell types and provide estimates of cell type populations in specific brain regions or circuits. The ultimate goal is to map cell types onto a brain atlas, demonstrating utility and scalability for a future comprehensive cell census of the human brain. Closing date for applications is March 13, 2014.

Opportunity ID: 249297

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-MH-14-215
Funding Opportunity Title::	BRAIN Initiative: Transformative Approaches for Cell-Type Classification in the Brain (U01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.113 — Environmental Health
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Dec 17, 2013
Last Updated Date::
Original Closing Date for Applications::	Mar 13, 2014
Current Closing Date for Applications::	Mar 13, 2014
Archive Date::	Apr 13, 2014
Estimated Total Program Funding::	$ 10,000,000
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Small businesses

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This funding opportunity announcement, in support of the NIH Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative aims to pilot classification strategies to generate a systematic inventory/cell census of cell types in the brain. Pilot projects are sought that would 1) provide cell census data in the whole brain, a brain region, or a significant functional circuit in the vertebrate nervous system; 2) integrate molecular identity of cell types with connectivity, morphology, and location; 3) apply statistical methods for creating a taxonomy of cell types based on molecular identity and connectivity; 4) provide realistic estimates on the number/percentage of defined cell types in specific region(s) and/or circuit(s); and 5) provide a basis to map cell types based on molecular identity and connectivity onto a reference brain atlas. These pilot projects and methodologies should be designed to demonstrate their utility and scalability to ultimately complete a comprehensive cell census of the human brain in the future.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	FORMS-C
Competition Title:	Forms-C
Opportunity Package ID:	PKG00191113
Opening Date:	Feb 13, 2014
Closing Date:	Mar 13, 2014
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3]