The National Institutes of Health (NIH) is offering a grant for Small Business Innovative Research (SBIR) projects aiming to create medium- to high-throughput assays for screening how toxicants impact pluripotent cell differentiation. Applications should focus on incorporating genetic diversity and assessing chemically-induced biological activities to prioritize chemicals for further evaluation. The developed assays will enhance understanding of toxicological effects, establish predictive models for biological responses, and investigate the impact of genetic diversity on toxicological outcomes. Closing date for submission is February 14, 2013.
Opportunity ID: 205853
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-ES-13-003 |
| Funding Opportunity Title:: | Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR [R43]) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Environment |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.113 — Environmental Health |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Nov 06, 2012 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Feb 14, 2013 |
| Current Closing Date for Applications:: | Feb 14, 2013 |
| Archive Date:: | Mar 17, 2013 |
| Estimated Total Program Funding:: | $ 2,500,000 |
| Award Ceiling:: | $225,000 |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Small businesses |
| Additional Information on Eligibility:: |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful. These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.113 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | Adobe-Forms-B2 |
| Opportunity Package ID: | PKG00151131 |
| Opening Date: | Jan 14, 2013 |
| Closing Date: | Feb 14, 2013 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] SBIR/STTR_Information [V1.1] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS Cover Letter [V1.2] |
Packages
| Assistance Listings | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions | Who Can Apply: | |
|---|---|---|---|---|---|---|---|---|
| 93.113 | ADOBE-FORMS-B2 | Adobe-Forms-B2 | PKG00151131 | Jan 14, 2013 | Feb 14, 2013 | View | eRA Commons Help Desk | Organization Applicants |