This grant, issued by the National Cancer Institute (NCI) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), aims to advance a mechanistic understanding of microflora influences on Gastro-Intestinal (GI) carcinogenesis. It encourages innovative, multidisciplinary research leveraging large, meta-omic data sets to identify critical microbial activities linked to GI cancer development. Applicants should integrate existing data or generate new data, including comprehensive gene and protein analyses (e.g., DNA sequence, post-translational modifications, secreted signals, and host-microbe protein interactions). The core purpose is to unravel how individual microbial species or communities contribute to GI carcinogenesis.
Opportunity ID: 158653
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-12-140 |
| Funding Opportunity Title: | Role of the Microflora in the Etiology of Gastro-Intestinal Cancer (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Mar 26, 2012 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 04, 2014 |
| Current Closing Date for Applications: | Mar 04, 2014 |
| Archive Date: | Apr 04, 2014 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) County governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments City or township governments Private institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA), encourages innovative multidisciplinary research projects that will advance our mechanistic understanding of microflora influences on Gastro-Intestinal (GI) carcinogenesis. This FOA seeks applications that leverage and integrate information from large, meta-omic data sets to guide studies that identify critical microbial activities that can be mechanistically linked to GI carcinogenesis. Applicants may draw from existing large data sets, and may also propose to generate appropriate new data, including but not limited to data from both gene and protein analysis, such as DNA sequence and copy number, post-translational modifications, secreted signals, and protein-protein interaction data between host factors and individual microbial species, or communities of microbes. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-12-140.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00110910 | Jun 02, 2012 | Sep 24, 2013 | View | |
| FORMS-C | Use for due dates after 9/24/2013. | PKG00180649 | Sep 08, 2013 | Mar 04, 2014 | View |
Package 1
Mandatory forms
158653 RR_SF424_1_2-1.2.pdf
158653 PerformanceSite_1_4-1.4.pdf
158653 RR_OtherProjectInfo_1_3-1.3.pdf
158653 RR_KeyPersonExpanded_1_2-1.2.pdf
158653 PHS398_CoverPageSupplement_1_4-1.4.pdf
158653 PHS398_ResearchPlan_1_3-1.3.pdf
158653 PHS398_Checklist_1_3-1.3.pdf
Optional forms
158653 RR_SubawardBudget30-1.2.pdf
158653 PHS398_ModularBudget_1_2-1.2.pdf
158653 RR_Budget-1.1.pdf
158653 PHS_CoverLetter_1_2-1.2.pdf
Package 2
Mandatory forms
158653 RR_SF424_2_0-2.0.pdf
158653 PHS398_ResearchPlan_2_0-2.0.pdf
158653 PHS398_CoverPageSupplement_2_0-2.0.pdf
158653 RR_KeyPersonExpanded_2_0-2.0.pdf
158653 RR_OtherProjectInfo_1_3-1.3.pdf
158653 PerformanceSite_2_0-2.0.pdf
Optional forms
158653 RR_SubawardBudget30_1_3-1.3.pdf
158653 PlannedReport-1.0.pdf
158653 PHS398_CumulativeInclusionReport-1.0.pdf
158653 PHS398_ModularBudget_1_2-1.2.pdf
158653 RR_Budget_1_3-1.3.pdf