This grant, offered by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institute of Nursing Research (NINR), and the Office of Dietary Supplements (ODS) of the National Institutes of Health (NIH), is for validating candidate biomarkers related to human diseases. Specifically, it targets conditions of the liver, kidney, urological tract, digestive and hematologic systems, endocrine and metabolic disorders, diabetes, and obesity, where current biomarkers are invasive, expensive, or non-existent. The purpose is to establish reliable assays for validated markers or provide new technologies for monitoring. This initiative aims to advance translational research and replace prohibitive clinical end points, focusing on validation rather than biomarker discovery projects.
Opportunity ID: 47798
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-204 |
| Funding Opportunity Title: | Development and Validation of Disease Biomarkers (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 04, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2012 |
| Current Closing Date for Applications: | Sep 07, 2012 |
| Archive Date: | Oct 08, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Private institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Independent school districts Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This Funding Opportunity Announcement (FOA) issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute of Nursing Research (NINR), and the Office of Dietary Supplements (ODS) of the National Institutes of Health, will provide resources to validate candidate biomarkers for well-defined human diseases of the liver, kidney, urological tract, and digestive and hematologic systems, as well as endocrine and metabolic disorders, diabetes and its complications, and obesity, for which there are no or very few biomarkers, or for which standard biomarkers are currently prohibitively invasive or expensive. A biomarker is an indicator of a disease process, and could replace hard clinical end points as a measure of the effect of new therapies. Appropriate studies will validate candidate biomarkers in well-defined patient populations, provide new technologies to monitor biomarkers or establish reliable assays for validated markers. Progress in this area has the potential to advance translational research related to efficacy of treatments and bio-behavioral interventions. This FOA is not appropriate for biomarker discovery projects. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. Developmental/Exploratory Research (R21) applications within the scientific scope of the FOA can be submitted in response to the NIH Parent R21 PA http://grants.nih.gov/grants/guide/pa-files/PA-06-181.html. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-204.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00021938 | Oct 15, 2010 | Sep 07, 2012 | View | |
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00012483 | Sep 05, 2009 | Feb 20, 2010 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00014698 | Dec 21, 2009 | Oct 15, 2010 | View |
Package 1
Mandatory forms
47798 RR_SF424_1_2-1.2.pdf
47798 RR_OtherProjectInfo_1_3-1.3.pdf
47798 RR_KeyPersonExpanded_1_2-1.2.pdf
47798 PerformanceSite_1_4-1.4.pdf
47798 PHS398_ResearchPlan_1_3-1.3.pdf
47798 PHS398_CoverPageSupplement_1_4-1.4.pdf
47798 PHS398_Checklist_1_3-1.3.pdf
Optional forms
47798 RR_Budget-1.1.pdf
47798 RR_SubawardBudget-1.2.pdf
47798 PHS_CoverLetter_1_2-1.2.pdf
47798 PHS398_ModularBudget-1.1.pdf
Package 2
Mandatory forms
47798 RR_SF424-1.1.pdf
47798 RR_KeyPersonExpanded-1.1.pdf
47798 RR_OtherProjectInfo-1.1.pdf
47798 RR_PerformanceSite-1.1.pdf
47798 PHS398_CoverPageSupplement-1.1.pdf
47798 PHS398_ResearchPlan-1.1.pdf
47798 PHS398_Checklist-1.1.pdf
Optional forms
47798 PHS398_CoverLetter-1.1.pdf
47798 PHS398_ModularBudget-1.1.pdf
47798 RR_Budget-1.1.pdf
47798 RR_SubawardBudget-1.2.pdf
Package 3
Mandatory forms
47798 RR_SF424_1_2-1.2.pdf
47798 PerformanceSite_1_3-1.3.pdf
47798 RR_OtherProjectInfo_1_2-1.2.pdf
47798 RR_KeyPersonExpanded_1_2-1.2.pdf
47798 PHS398_CoverPageSupplement_1_4-1.4.pdf
47798 PHS398_ResearchPlan_1_3-1.3.pdf
47798 PHS398_Checklist_1_3-1.3.pdf
Optional forms
47798 PHS_CoverLetter_1_2-1.2.pdf
47798 PHS398_ModularBudget-1.1.pdf
47798 RR_Budget-1.1.pdf
47798 RR_SubawardBudget-1.2.pdf
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