The Glioblastoma Therapeutics Network (GTN), an initiative likely supported by a major health research department, is offering this significant grant opportunity. This grant is designed to foster the development of novel and effective therapeutic agents specifically targeting adult glioblastoma (GBM). A core purpose is to identify and test compounds capable of effectively penetrating the blood-brain barrier (BBB), a critical challenge in GBM treatment. Multi-institution teams are invited to apply, with the expectation of driving therapeutic agents from initial pre-clinical research through Investigational New Drug (IND) studies and into pilot clinical trials in humans. This collaborative effort aims to accelerate the translation of promising discoveries into tangible clinical improvements for GBM patients.
Opportunity ID: 328818
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-20-047 |
| Funding Opportunity Title: | Glioblastoma Therapeutics Network (U19 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 27, 2020 |
| Last Updated Date: | Aug 27, 2020 |
| Original Closing Date for Applications: | Nov 19, 2020 |
| Current Closing Date for Applications: | Nov 19, 2020 |
| Archive Date: | Dec 25, 2020 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts State governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Public housing authorities/Indian housing authorities Special district governments For profit organizations other than small businesses County governments City or township governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The overall goal of this funding opportunity announcement (FOA) is to improve the treatment of adult glioblastoma (GBM) by developing novel effective agents that can cross the blood-brain barrier (BBB) and testing them in the clinic. To implement this concept, multi-institution teams are invited to participate in the Glioblastoma Therapeutics Network (GTN). Each GTN team will be capable of driving therapeutic agent(s) from pre-clinical development, through IND studies, into pilot clinical studies in humans. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-20-047.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00263122 | Oct 19, 2020 | Nov 19, 2020 | View |
Package 1
Mandatory forms
328818 RR_SF424_2_0-2.0.pdf
328818 PHS398_CoverPageSupplement_5_0-5.0.pdf
328818 RR_OtherProjectInfo_1_4-1.4.pdf
328818 PerformanceSite_2_0-2.0.pdf
328818 RR_KeyPersonExpanded_2_0-2.0.pdf
328818 PHS398_ResearchPlan_4_0-4.0.pdf
328818 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
328818 PHS_Additional_IndirectCosts-1.0.pdf
328818 PHS_AssignmentRequestForm_3_0-3.0.pdf
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