Opportunity ID: 347327

General Information

Document Type: Grants Notice
Funding Opportunity Number: PD-23-7236
Funding Opportunity Title: Biophotonics
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
Assistance Listings: 47.041 — Engineering
Cost Sharing or Matching Requirement: No
Version: Synopsis 3
Posted Date: Apr 05, 2023
Last Updated Date: Feb 24, 2024
Original Closing Date for Applications: – Proposals accepted anytime
Current Closing Date for Applications: – Proposals accepted anytime
Archive Date:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: U.S. National Science Foundation
Description: TheBiophotonicsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiosensingprogram; 2) theCellular and Biochemical Engineeringprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram.

The goal of theBiophotonicsprogram is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals.

Research topics in this program include:

  • Imaging in the second near infrared window:Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging.
  • Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells.Pushing the envelope of optical sensing to the limits of detection, resolution, and identification.
  • Low coherence sensing at the nanoscale: Low coherence enhanced backscattering (LEBS). N-dimensional elastic light scattering.Angle-resolved low coherence interferometry for early cancer detection (dysplasia).
  • Neurophotonics:Studies of photon activation of neurons at the interface of nanomaterials attached to cells. Development and application of biocompatible photonic tools such as parallel interfaces and interconnects for communicating and control of neural networks.
  • Microphotonics and nanophotonics:Development and application of novel nanoparticle fluorescent quantum-dots. Sensitive, multiplexed, high-throughput characterization of macromolecular properties of cells.Nanomaterials and nanodevices for biomedicine.
  • Optogenetics: Novel research in employing light-activated channels and enzymes for manipulation of neural activity with temporal precision. Utilizing nanophotonics, nanofibers, and genetic techniques for mapping and studying in real-time physiological processes in organs such as the brain and heart.

Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review.

INFORMATION COMMON TO MOST CBET PROGRAMS

Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal.

The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.

Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in theCAREER program description.

Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal.

Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals.

Compliance: Proposals that are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review.

Link to Additional Information: NSF Program Desccription PD-23-7236
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NSF grants.gov support
grantsgovsupport@nsf.gov
Email:grantsgovsupport@nsf.gov

Version History

Version Modification Description Updated Date
. Feb 24, 2024
. Apr 05, 2023
Apr 05, 2023

DISPLAYING: Synopsis 3

General Information

Document Type: Grants Notice
Funding Opportunity Number: PD-23-7236
Funding Opportunity Title: Biophotonics
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
Assistance Listings: 47.041 — Engineering
Cost Sharing or Matching Requirement: No
Version: Synopsis 3
Posted Date: Apr 05, 2023
Last Updated Date: Feb 24, 2024
Original Closing Date for Applications: – Proposals accepted anytime
Current Closing Date for Applications: – Proposals accepted anytime
Archive Date:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: U.S. National Science Foundation
Description: TheBiophotonicsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiosensingprogram; 2) theCellular and Biochemical Engineeringprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram.

The goal of theBiophotonicsprogram is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals.

Research topics in this program include:

  • Imaging in the second near infrared window:Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging.
  • Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells.Pushing the envelope of optical sensing to the limits of detection, resolution, and identification.
  • Low coherence sensing at the nanoscale: Low coherence enhanced backscattering (LEBS). N-dimensional elastic light scattering.Angle-resolved low coherence interferometry for early cancer detection (dysplasia).
  • Neurophotonics:Studies of photon activation of neurons at the interface of nanomaterials attached to cells. Development and application of biocompatible photonic tools such as parallel interfaces and interconnects for communicating and control of neural networks.
  • Microphotonics and nanophotonics:Development and application of novel nanoparticle fluorescent quantum-dots. Sensitive, multiplexed, high-throughput characterization of macromolecular properties of cells.Nanomaterials and nanodevices for biomedicine.
  • Optogenetics: Novel research in employing light-activated channels and enzymes for manipulation of neural activity with temporal precision. Utilizing nanophotonics, nanofibers, and genetic techniques for mapping and studying in real-time physiological processes in organs such as the brain and heart.

Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review.

INFORMATION COMMON TO MOST CBET PROGRAMS

Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal.

The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.

Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in theCAREER program description.

Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal.

Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals.

Compliance: Proposals that are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review.

Link to Additional Information: NSF Program Desccription PD-23-7236
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NSF grants.gov support
grantsgovsupport@nsf.gov
Email:grantsgovsupport@nsf.gov

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: PD-23-7236
Funding Opportunity Title: Biophotonics
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
Assistance Listings: 47.041 — Engineering
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Apr 05, 2023
Last Updated Date: May 20, 2023
Original Closing Date for Applications:
Current Closing Date for Applications: – Proposals accepted anytime
Archive Date:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: U.S. National Science Foundation
Description: TheBiophotonicsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiosensingprogram; 2) theCellular and Biochemical Engineeringprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram.

The goal of theBiophotonicsprogram is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals.

Research topics in this program include:

  • Imaging in the second near infrared window:Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging.
  • Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells.Pushing the envelope of optical sensing to the limits of detection, resolution, and identification.
  • Low coherence sensing at the nanoscale: Low coherence enhanced backscattering (LEBS). N-dimensional elastic light scattering.Angle-resolved low coherence interferometry for early cancer detection (dysplasia).
  • Neurophotonics:Studies of photon activation of neurons at the interface of nanomaterials attached to cells. Development and application of biocompatible photonic tools such as parallel interfaces and interconnects for communicating and control of neural networks.
  • Microphotonics and nanophotonics:Development and application of novel nanoparticle fluorescent quantum-dots. Sensitive, multiplexed, high-throughput characterization of macromolecular properties of cells.Nanomaterials and nanodevices for biomedicine.
  • Optogenetics: Novel research in employing light-activated channels and enzymes for manipulation of neural activity with temporal precision. Utilizing nanophotonics, nanofibers, and genetic techniques for mapping and studying in real-time physiological processes in organs such as the brain and heart.

Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review.

INFORMATION COMMON TO MOST CBET PROGRAMS

Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal.

The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.

Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in theCAREER program description.

Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal.

Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals.

Compliance: Proposals that are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review.

Link to Additional Information: NSF Program Desccription PD-23-7236
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NSF grants.gov support
grantsgovsupport@nsf.gov
Email:grantsgovsupport@nsf.gov

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: PD-23-7236
Funding Opportunity Title: Biophotonics
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Science and Technology and other Research and Development
Category Explanation:
Expected Number of Awards:
Assistance Listings: 47.041 — Engineering
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Apr 05, 2023
Last Updated Date: Apr 05, 2023
Original Closing Date for Applications:
Current Closing Date for Applications: – Proposals accepted anytime
Archive Date:
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility”
Additional Information on Eligibility:

Additional Information

Agency Name: U.S. National Science Foundation
Description: TheBiophotonicsprogram is part of the Engineering Biology and Health cluster, which also includes: 1) theBiosensingprogram; 2) theCellular and Biochemical Engineeringprogram; 3) theDisability and Rehabilitation Engineeringprogram; and 4) theEngineering of Biomedical Systemsprogram.

The goal of theBiophotonicsprogram is to explore the research frontiers in photonics principles, engineering and technology that are relevant for critical problems in fields of medicine, biology and biotechnology. Fundamental engineering research and innovation in photonics is required to lay the foundations for new technologies beyond those that are mature and ready for application in medical diagnostics and therapies. Advances are needed in nanophotonics, optogenetics, contrast and targeting agents, ultra-thin probes, wide field imaging, and rapid biomarker screening. Low cost and minimally invasive medical diagnostics and therapies are key motivating application goals.

Research topics in this program include:

  • Imaging in the second near infrared window:Research that advances medical applications of biophotonics in the second near-infrared window (NIR-II: 1,000-1,700 nm) in which biological tissues are transparent up to several centimeters in depth, making this spectral window ideal for deep tissue imaging.
  • Macromolecule markers: Innovative methods for labeling of macromolecules. Novel compositions of matter. Methods of fabrication of multicolor probes that could be used for marking and detection of specific pathological cells.Pushing the envelope of optical sensing to the limits of detection, resolution, and identification.
  • Low coherence sensing at the nanoscale: Low coherence enhanced backscattering (LEBS). N-dimensional elastic light scattering.Angle-resolved low coherence interferometry for early cancer detection (dysplasia).
  • Neurophotonics:Studies of photon activation of neurons at the interface of nanomaterials attached to cells. Development and application of biocompatible photonic tools such as parallel interfaces and interconnects for communicating and control of neural networks.
  • Microphotonics and nanophotonics:Development and application of novel nanoparticle fluorescent quantum-dots. Sensitive, multiplexed, high-throughput characterization of macromolecular properties of cells.Nanomaterials and nanodevices for biomedicine.
  • Optogenetics: Novel research in employing light-activated channels and enzymes for manipulation of neural activity with temporal precision. Utilizing nanophotonics, nanofibers, and genetic techniques for mapping and studying in real-time physiological processes in organs such as the brain and heart.

Innovative proposals outside of these specific interest areas may be considered. However, prior to submission, it is recommended that the Principal Investigator contact the program director to avoid the possibility of the proposal being returned without review.

INFORMATION COMMON TO MOST CBET PROGRAMS

Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field. Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research. The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal.

The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.

Faculty Early Career Development(CAREER)program proposals are strongly encouraged. Award duration is five years. The submission deadline for Engineering CAREER proposals is in July every year. Learn more in theCAREER program description.

Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal.

Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission.Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals.

Compliance: Proposals that are not compliant with theProposal & Award Policies & Procedures Guide (PAPPG)will be returned without review.

Link to Additional Information: NSF Program Desccription PD-23-7236
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NSF grants.gov support
grantsgovsupport@nsf.gov
Email:grantsgovsupport@nsf.gov

Related Documents

Packages

Agency Contact Information: NSF grants.gov support
grantsgovsupport@nsf.gov
Email: grantsgovsupport@nsf.gov
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
PKG00281003 Apr 05, 2023 Sep 30, 2025 View

Package 1

Mandatory forms

347327 RR_SF424_5_0-5.0.pdf

347327 NSF_CoverPage_2_3-2.3.pdf

347327 NSF_KeyPersonExpanded_3_3-3.3.pdf

347327 RR_Budget_3_0-3.0.pdf

347327 PerformanceSite_4_0-4.0.pdf

347327 RR_OtherProjectInfo_1_4-1.4.pdf

Optional forms

347327 NSF_DeviationAuthorization-1.1.pdf

347327 NSF_SuggestedReviewers-1.1.pdf

347327 RR_SubawardBudget_3_0-3.0.pdf

2025-07-10T15:01:58-05:00

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