This National Institute of Mental Health (NIMH) grant invites applications for research focused on understanding the mechanisms of HIV-1 persistence within myeloid cells and developing targeted strategies to eradicate these reservoirs from the central nervous system. The funding supports both basic and translational research, applicable in domestic and international settings. While multidisciplinary teams and collaborative alliances are encouraged, they are not mandatory. This opportunity primarily uses the R21 grant mechanism, which is ideal for high-risk, high-payoff projects or those with limited preliminary data. Applicants with substantial preliminary data may consider the R01 mechanism. The grant aims to advance knowledge and interventions against HIV-1 brain reservoirs.
Opportunity ID: 329219
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-MH-20-702 |
| Funding Opportunity Title: | Role of Myeloid Cells in Persistence and Eradication of HIV-1 Reservoirs from the Brain (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 25, 2020 |
| Last Updated Date: | Sep 25, 2020 |
| Original Closing Date for Applications: | Jan 08, 2021 |
| Current Closing Date for Applications: | Jan 08, 2021 |
| Archive Date: | Feb 13, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Independent school districts For profit organizations other than small businesses Public housing authorities/Indian housing authorities County governments Private institutions of higher education Small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites research grant applications studying mechanisms of HIV-1 persistence in myeloid cells and strategies to target this reservoir in the central nervous system. Basic and translational research in domestic and international settings are of interest. Multidisciplinary research teams and collaborative alliances are encouraged but not required. RFA-MH-20-701uses the R01 grant mechanism whileRFA-MH-20-702uses the R21 mechanism. High risk/high payoff projects that lack preliminary data or utilize existing data may be most appropriate for the R21 mechanism, while applicants with preliminary data may wish to apply using the R01 mechanism. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-MH-20-702.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00263582 | Dec 08, 2020 | Jan 08, 2021 | View |
Package 1
Mandatory forms
329219 RR_SF424_2_0-2.0.pdf
329219 PHS398_CoverPageSupplement_5_0-5.0.pdf
329219 RR_OtherProjectInfo_1_4-1.4.pdf
329219 PerformanceSite_2_0-2.0.pdf
329219 RR_KeyPersonExpanded_2_0-2.0.pdf
329219 PHS398_ResearchPlan_4_0-4.0.pdf
329219 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
329219 RR_Budget_1_4-1.4.pdf
329219 RR_SubawardBudget30_1_4-1.4.pdf
329219 PHS398_ModularBudget_1_2-1.2.pdf
329219 PHS_AssignmentRequestForm_3_0-3.0.pdf
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