This National Institutes of Health (NIH) R21 grant is for supporting mechanistic ancillary studies within ongoing clinical projects. Its purpose is to investigate the biological processes and pathways underlying observed clinical outcomes. The grant aims to provide deeper insights into the ‘how’ and ‘why’ of disease progression or treatment responses. Researchers should leverage existing patient cohorts, biospecimens, and data from active clinical trials or observational studies. This R21 opportunity funds exploratory, developmental research, explicitly excluding new clinical trials, to advance understanding of human health and disease mechanisms.
Opportunity ID: 329555
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-21-054 |
| Funding Opportunity Title: | Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 22, 2020 |
| Last Updated Date: | Nov 21, 2022 |
| Original Closing Date for Applications: | Dec 02, 2022 |
| Current Closing Date for Applications: | Nov 21, 2022 |
| Archive Date: | Dec 21, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $250,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities County governments Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-21-054.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| updated close date | Nov 21, 2022 | |
| Oct 22, 2020 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-21-054 |
| Funding Opportunity Title: | Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Oct 22, 2020 |
| Last Updated Date: | Nov 21, 2022 |
| Original Closing Date for Applications: | Dec 02, 2022 |
| Current Closing Date for Applications: | Nov 21, 2022 |
| Archive Date: | Dec 21, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $250,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities County governments Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-21-054.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-21-054 |
| Funding Opportunity Title: | Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 22, 2020 |
| Last Updated Date: | Oct 22, 2020 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Dec 02, 2022 |
| Archive Date: | Jan 07, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $250,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments County governments Independent school districts Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Mechanistic Ancillary Studies to Ongoing Clinical Projects (R21 Clinical Trial Not Allowed) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-21-054.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
Folder 329555 Full Announcement-PAR-21-054 -> PAR-21-054-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00263893 | Feb 18, 2021 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00270282 | Nov 16, 2021 | Nov 22, 2022 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00278119 | Nov 08, 2022 | Nov 22, 2022 | View |
Package 1
Mandatory forms
329555 RR_SF424_2_0-2.0.pdf
329555 PHS398_CoverPageSupplement_5_0-5.0.pdf
329555 RR_OtherProjectInfo_1_4-1.4.pdf
329555 PerformanceSite_2_0-2.0.pdf
329555 RR_KeyPersonExpanded_2_0-2.0.pdf
329555 PHS398_ResearchPlan_4_0-4.0.pdf
329555 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
329555 RR_Budget_1_4-1.4.pdf
329555 RR_SubawardBudget30_1_4-1.4.pdf
329555 PHS398_ModularBudget_1_2-1.2.pdf
329555 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
329555 RR_SF424_5_0-5.0.pdf
329555 PHS398_CoverPageSupplement_5_0-5.0.pdf
329555 RR_OtherProjectInfo_1_4-1.4.pdf
329555 PerformanceSite_4_0-4.0.pdf
329555 RR_KeyPersonExpanded_4_0-4.0.pdf
329555 PHS398_ResearchPlan_4_0-4.0.pdf
329555 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
329555 RR_Budget_3_0-3.0.pdf
329555 RR_SubawardBudget30_3_0-3.0.pdf
329555 PHS398_ModularBudget_1_2-1.2.pdf
329555 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
329555 RR_SF424_5_0-5.0.pdf
329555 PHS398_CoverPageSupplement_5_0-5.0.pdf
329555 RR_OtherProjectInfo_1_4-1.4.pdf
329555 PerformanceSite_4_0-4.0.pdf
329555 RR_KeyPersonExpanded_4_0-4.0.pdf
329555 PHS398_ResearchPlan_5_0-5.0.pdf
329555 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
329555 RR_Budget_3_0-3.0.pdf
329555 RR_SubawardBudget30_3_0-3.0.pdf
329555 PHS398_ModularBudget_1_2-1.2.pdf
329555 PHS_AssignmentRequestForm_3_0-3.0.pdf
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