This National Cancer Institute (NCI) R33 grant is for the advanced development and validation of technologies improving biospecimen quality and utility for downstream molecular analyses in cancer research. It addresses pre-analytical variations in collection, processing, handling, and storage. The grant supports tools, devices, and methods to assess sample quality, preserve integrity, and establish robust quality control criteria. Applicants must demonstrate established proof-of-principle for their proposed technology or methodology. This grant specifically funds technological innovation, not novel biological questions using established technologies.
Opportunity ID: 49990
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | RFA-CA-10-002 |
Funding Opportunity Title: | Validation and Advanced Development of Emerging Technologies in Biospecimen Science (R33) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Grant |
Category of Funding Activity: | Education Health |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Oct 26, 2009 |
Last Updated Date: | – |
Original Closing Date for Applications: | Sep 30, 2010 |
Current Closing Date for Applications: | Sep 30, 2010 |
Archive Date: | Oct 31, 2010 |
Estimated Total Program Funding: | $2,250,000 |
Award Ceiling: | $300,000 |
Award Floor: | – |
Eligibility
Eligible Applicants: | Public and State controlled institutions of higher education Small businesses For profit organizations other than small businesses State governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Non-domestic (non-U.S.) Entities (Foreign Organizations); U.S. Territory or Possession. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | Purpose. This Funding Opportunity Announcement (FOA), issued by the National Cancer Institute (NCI), National Institutes of Health (NIH), solicits grant applications proposing technically innovative feasibility studies focused on the advanced development and validation of cancer-relevant technologies that address the issues related to pre-analytical variations in the collection, processing, handling, and storage of biospecimens or its derivatives. The overall goal is to develop technologies capable of interrogating and/or maximizing the quality and utility of biospecimens or their derived samples for downstream molecular analyses. This FOA will support the development of tools, devices, instrumentation, and associated methods to assess sample quality, preserve/protect sample integrity, and establish verification criteria for quality assessment/quality control and handling under diverse conditions. This FOA solicits R33 applications; this mechanism is suitable for projects where proof-of-principle of the proposed technology or methodology has already been established and supportive preliminary data are available. Projects proposing to use established technologies where the novelty resides in the biological or clinical question being pursued is an example of a topic not appropriate for this solicitation and will be returned as non-responsive. This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program. Mechanism of Support. This FOA will utilize the R33 grant mechanism and runs in parallel with a FOA of identical scientific scope, RFA-CA-10-001 that solicits applications under the NIH Exploratory/Developmental R21 grant mechanism. |
Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-10-002.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
Version | Modification Description | Updated Date |
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Related Documents
There are no related documents on this grant.
Packages
Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00015613 | Jan 23, 2010 | Sep 30, 2010 | View |
Package 1
Mandatory forms
49990 RR_SF424_1_2-1.2.pdf
49990 PerformanceSite_1_3-1.3.pdf
49990 RR_OtherProjectInfo_1_2-1.2.pdf
49990 RR_KeyPersonExpanded_1_2-1.2.pdf
49990 RR_Budget-1.1.pdf
49990 PHS398_CoverPageSupplement_1_4-1.4.pdf
49990 PHS398_ResearchPlan_1_3-1.3.pdf
49990 PHS398_Checklist_1_3-1.3.pdf
Optional forms
49990 PHS_CoverLetter_1_2-1.2.pdf
49990 RR_SubawardBudget-1.2.pdf