The National Eye Institute (NEI) offers UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, including human gene-transfer, stem cell therapy, and other complex or high-risk clinical trials. These multifaceted projects are of high public health significance and require clear organizational structure with careful oversight and monitoring. This grant specifically focuses on evaluating interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or comparing the effectiveness of two or more established interventions. This Notice of Funding Opportunity encourages applications for the Chair’s grant, which should detail the scientific rationale, study aims, and significance of the proposed research project, fostering advancements in vision care.
Opportunity ID: 348386
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-23-209 |
| Funding Opportunity Title: | NEI Collaborative Clinical Vision Research: Chair’s Grant (UG1-Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.867 — Vision Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 25, 2023 |
| Last Updated Date: | May 25, 2023 |
| Original Closing Date for Applications: | May 25, 2026 |
| Current Closing Date for Applications: | May 25, 2026 |
| Archive Date: | Jun 30, 2026 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses County governments Independent school districts Public and State controlled institutions of higher education Private institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NEI uses UG1 cooperative agreement awards to support investigator-initiated large-scale clinical trials, human gene-transfer, stem cell therapy trials, and other complex or high resource- or safety-risk clinical trials. These projects are multifaceted and of high public health significance requiring clear delineation of study organization including roles and responsibilities and require careful performance oversight and monitoring. For purposes of this Notice of Funding Opportunity (NOFO), the proposed study must be intended to evaluate interventions aimed at screening, diagnosing, preventing, or treating vision disorders, or to compare the effectiveness of two or more established interventions. The NEI UG1-supported studies are typically funded as a group of single-component companion grant awards including the Chairs Grant, the Coordinating Center, and Resource Centers, when appropriate. Specifically, this NOFO encourages applications for the Chair’s grant, which includes the scientific rationale, study aims and significance of the research project. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-23-209.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 348386 Full Announcement-PAR-23-209 -> PAR-23-209-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00281891 | Jun 12, 2023 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289232 | Nov 27, 2024 | May 25, 2026 | View |
Package 1
Mandatory forms
348386 RR_SF424_5_0-5.0.pdf
348386 PHS398_CoverPageSupplement_5_0-5.0.pdf
348386 RR_OtherProjectInfo_1_4-1.4.pdf
348386 PerformanceSite_4_0-4.0.pdf
348386 RR_KeyPersonExpanded_4_0-4.0.pdf
348386 RR_Budget_3_0-3.0.pdf
348386 PHS398_ResearchPlan_5_0-5.0.pdf
348386 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
348386 RR_SubawardBudget30_3_0-3.0.pdf
348386 PHS_AssignmentRequestForm_4_0-4.0.pdf
Package 2
Mandatory forms
348386 RR_SF424_5_0-5.0.pdf
348386 PHS398_CoverPageSupplement_5_0-5.0.pdf
348386 RR_OtherProjectInfo_1_4-1.4.pdf
348386 PerformanceSite_4_0-4.0.pdf
348386 RR_KeyPersonExpanded_4_0-4.0.pdf
348386 RR_Budget_3_0-3.0.pdf
348386 PHS398_ResearchPlan_5_0-5.0.pdf
348386 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
348386 RR_SubawardBudget30_3_0-3.0.pdf
348386 PHS_AssignmentRequestForm_3_0-3.0.pdf
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