The National Human Genome Research Institute (NHGRI) is renewing its Human Genome Reference Program (HGRP) and offering this grant to develop High Quality Human Reference Genomes (HQRG). This initiative aims to produce 200 new, very high-quality haplotype-resolved human genome assemblies. These genomes will be derived from diverse participants, consented for open access data release, and are crucial for the evolving human pangenome reference. The grant also supports an embedded team of ethical, legal, and social issues (ELSI) scholars. This ELSI team will collaborate with the consortium to navigate complex topics like consent, data release, and data sovereignty. This is a limited competition opportunity, exclusively for organizations previously funded under RFA-HG-19-002.
Opportunity ID: 348806
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-23-024 |
| Funding Opportunity Title: | Limited Competition: High Quality Reference Genomes (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 20, 2023 |
| Last Updated Date: | Jun 20, 2023 |
| Original Closing Date for Applications: | Aug 15, 2023 |
| Current Closing Date for Applications: | Aug 15, 2023 |
| Archive Date: | Sep 20, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses State governments County governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities City or township governments Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Private institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Human Genome Research Institute (NHGRI) will renew the NHGRI Human Genome Reference Program (HGRP). This FOA seeks applications for the production of High Quality Human Reference Genomes (HQRG) as one of three components of the renewed HGRP. The HQRG component will lead the prioritization and selection of samples from diverse participants consented for open access data release, and, with those samples, produce 200 new, very high-quality haplotype-resolved human genome assemblies for inclusion in the human pangenome reference. The HQRG component will also include a team of ethical, legal and social issues scholars who will be embedded in the overall HGRP. This team will be integrated with the consortium to help identify and navigate topics raised by the development of a human pangenome resource, including consent, data release and sovereignty, definitions of diversity, and others that may arise over time. This is a limited competition RFA. Only recipient organizations funded under RFA-HG-19-002 are eligible to apply. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-23-024.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 348806 Full Announcement-RFA-HG-23-024 -> RFA-HG-23-024-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282226 | Jul 14, 2023 | Aug 15, 2023 | View |
Package 1
Mandatory forms
348806 RR_SF424_5_0-5.0.pdf
348806 PHS398_CoverPageSupplement_5_0-5.0.pdf
348806 RR_OtherProjectInfo_1_4-1.4.pdf
348806 PerformanceSite_4_0-4.0.pdf
348806 RR_KeyPersonExpanded_4_0-4.0.pdf
348806 RR_Budget_3_0-3.0.pdf
348806 PHS398_ResearchPlan_5_0-5.0.pdf
348806 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
348806 RR_SubawardBudget30_3_0-3.0.pdf
348806 PHS_AssignmentRequestForm_3_0-3.0.pdf
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