The U.S. Department of Energy’s Office of Biological and Environmental Research (BER) offers this grant for Radiochemistry and Radionuclide Imaging Instrumentation research, aiming to develop novel, high-resolution imaging methodologies for dynamic biological processes. Its purpose is to support DOE’s bioenergy and bioremediation missions and create tools for nuclear medicine. BER invites proposals in Radiochemistry (improving radionuclide incorporation) and Radionuclide Imaging Instrumentation (designing advanced detection tools). These aim to enhance quantitative assessments and high-throughput screening of living systems, like plants. The research must significantly advance basic scientific understanding relevant to DOE’s mission.
Opportunity ID: 51470
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | DE-FOA-0000265 |
| Funding Opportunity Title: | Radiochemistry and Radionuclide Imaging Instrumentation Research |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 81.049 — Office of Science Financial Assistance Program |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 02, 2010 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 19, 2010 |
| Current Closing Date for Applications: | Apr 19, 2010 |
| Archive Date: | Sep 30, 2010 |
| Estimated Total Program Funding: | $6,000,000 |
| Award Ceiling: | $400,000 |
| Award Floor: | $250,000 |
Eligibility
| Eligible Applicants: | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled “Additional Information on Eligibility” |
| Additional Information on Eligibility: | All types of domestic entities are eligible to apply as the lead institution, except other Federal agencies, Federally Funded Research and Development Center (FFRDC) Contractors, and nonprofit organizations described in section 501(c)(4) of the Internal Revenue Code of 1986 that engaged in lobbying activities after December 31, 1995. |
Additional Information
| Agency Name: | Chicago Service Center |
| Description: | The Office of Biological and Environmental Research (BER) of the Office of Science (SC), U.S. Department of Energy (DOE) advances world-class biological and environmental research programs and scientific facilities for DOE missions in energy, environment, and basic research. The Radiochemistry and Radionuclide Imaging Instrumentation Research program within BER, supports fundamental research for developing new methodologies for real-time, high-resolution imaging of dynamic biological processes in living systems. This research has two integrated goals: First, the research supports the DOE Science mission-related activities in bioenergy and bioremediation; Second, the fundamental methodologies developed under DOE-funded research may serve as tools leading to transformational new technologies for use in nuclear medicine research and applications supported by NIH and industry. Applicants are encouraged to meet these two goals. Responses to this Fu nding Opportunity Announcement (FOA) should address the development and use of highly innovative radiotracer chemistry or instrumentation technologies for quantitative in vivo measurement of site-specific chemical reactions, their spatial distributions and metabolic perturbations, and ensuing biological processes with a high degree of accuracy and sensitivity. BER hereby announces its interest in receiving applications for research grants in two topic areas, Radiochemistry and Radionuclide Imaging Instrumentation. In the area of Radiochemistry, BER invites applications for fundamental research to improve synthetic methodology for rapidly and efficiently incorporating radionuclides into a wide range of organic molecules. Approaches should use methods that allow dual or multiple labeling of targeting molecules for dual energy or hybrid imaging techniques in intact living systems and/or in vivo models. Development of microfluidics for synthesis and purification are also appropr iate. In the area of Radionuclide Imaging Instrumentation, BER invites applications to design and develop new or improved radionuclide detection and imaging instrumentation. These improvements should significantly increase the accuracy of quantitative assessments of the three dimensional spatial and temporal distribution of radiotracers in living systems, allow the screening of large numbers of intact living systems (e.g. plants), or the screening of cells to identify desirable characteristics. Development of instruments which allow simultaneous examination of biological systems using different modalities to improve understanding is also encouraged. Applications should focus on basic research that will significantly advance the current state of the science underpinning biological systems of importance to the mission of the DOE, and which may also have application in nuclear medicine. |
| Link to Additional Information: | FedConnect |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
Kimberlie J. Laing, Grant Analyst, 301-903-3026
kim.laing@science.doe.gov Prem C. Srivastava, Technical-Scientific Program Contact, 301-903-4071 prem.srivastava@science.doe.gov Email:kim.laing@science.doe.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | Kimberlie J. Laing, Grant Analyst, 301-903-3026 kim.laing@science.doe.gov Prem C. Srivastava, Technical-Scientific Program Contact, 301-903-4071 prem.srivastava@science.doe.gov Email: kim.laing@science.doe.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 81.049 | DE-FOA-0000265 | Radiochemistry and Radionuclide Imaging Instrumentation Research | PKG00016173 | Feb 02, 2010 | Apr 19, 2010 | View |
Package 1
Mandatory forms
51470 RR_SF424_1_2-1.2.pdf
51470 RR_Budget-1.1.pdf
51470 PerformanceSite_1_2-1.2.pdf
51470 RR_OtherProjectInfo_1_2-1.2.pdf
Optional forms
51470 RR_SubawardBudget-1.2.pdf
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