This grant, offered by the Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) program, is for developing innovative prophylactic countermeasures against bloodborne pathogens and bloodstream infections (BSI) associated with combat wounds. Current interventions, such as traditional antibiotics and antifungals, are often limited by toxicity, ineffectiveness, or delayed administration. The purpose of this funding is to create safe, effective, and broad-spectrum prophylaxes that protect recipients from a wide range of bloodborne bacteria and fungi, which are responsible for most BSI. Ultimately, this initiative seeks to prevent these critical infections for up to 144 hours, significantly enhancing patient outcomes in high-risk scenarios.
Opportunity ID: 348974
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | HR001123S0037 |
| Funding Opportunity Title: | Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Other Procurement Contract |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 12.910 — Research and Technology Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 28, 2023 |
| Last Updated Date: | Jul 25, 2023 |
| Original Closing Date for Applications: | Sep 27, 2023 See Full Announcement for details. |
| Current Closing Date for Applications: | Sep 27, 2023 See Full Announcement for details. |
| Archive Date: | Oct 27, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | All responsible sources capable of satisfying the Government’s needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information. |
Additional Information
| Agency Name: | DARPA – Biological Technologies Office |
| Description: | The Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) program will develop safe and effective prophylactic countermeasures to defeat bloodborne pathogens and prevent bloodstream infections (BSI) associated with combat wounds. The program will develop prophylactic countermeasures effective against both bacteria and fungi, pathogens that are responsible for the vast majority of BSI. State-of-the-art countermeasures to manage BSI include antifungals and antibiotics which can be toxic, ineffective, and be administered in an untimely manner. SHIELD will develop safe and effective broad-spectrum prophylaxes that will protect recipients from bloodborne bacteria and fungi and prevent BSI for up to 144 h. |
| Link to Additional Information: | SAM.gov Contract Opportunities |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
BAA Coordinator
SHIELD@darpa.mil Email:SHIELD@darpa.mil |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| To clarify the timeline for Milestone 2.1 deliverables. | Jul 25, 2023 | |
| Jun 28, 2023 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | HR001123S0037 |
| Funding Opportunity Title: | Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Other Procurement Contract |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 12.910 — Research and Technology Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jun 28, 2023 |
| Last Updated Date: | Jul 25, 2023 |
| Original Closing Date for Applications: | Sep 27, 2023 See Full Announcement for details. |
| Current Closing Date for Applications: | Sep 27, 2023 See Full Announcement for details. |
| Archive Date: | Oct 27, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | All responsible sources capable of satisfying the Government’s needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information. |
Additional Information
| Agency Name: | DARPA – Biological Technologies Office |
| Description: | The Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) program will develop safe and effective prophylactic countermeasures to defeat bloodborne pathogens and prevent bloodstream infections (BSI) associated with combat wounds. The program will develop prophylactic countermeasures effective against both bacteria and fungi, pathogens that are responsible for the vast majority of BSI. State-of-the-art countermeasures to manage BSI include antifungals and antibiotics which can be toxic, ineffective, and be administered in an untimely manner. SHIELD will develop safe and effective broad-spectrum prophylaxes that will protect recipients from bloodborne bacteria and fungi and prevent BSI for up to 144 h. |
| Link to Additional Information: | SAM.gov Contract Opportunities |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
BAA Coordinator
SHIELD@darpa.mil Email:SHIELD@darpa.mil |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | HR001123S0037 |
| Funding Opportunity Title: | Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement Other Procurement Contract |
| Category of Funding Activity: | Science and Technology and other Research and Development |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 12.910 — Research and Technology Development |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 28, 2023 |
| Last Updated Date: | Jun 28, 2023 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Sep 27, 2023 See Full Announcement for details. |
| Archive Date: | Oct 27, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | All responsible sources capable of satisfying the Government’s needs may submit a proposal that shall be considered by DARPA. See the Eligibility Information section of the BAA for more information. |
Additional Information
| Agency Name: | DARPA – Biological Technologies Office |
| Description: | The Synthetic Hemo-technologIEs to Locate and Disinfect (SHIELD) program will develop safe and effective prophylactic countermeasures to defeat bloodborne pathogens and prevent bloodstream infections (BSI) associated with combat wounds. The program will develop prophylactic countermeasures effective against both bacteria and fungi, pathogens that are responsible for the vast majority of BSI. State-of-the-art countermeasures to manage BSI include antifungals and antibiotics which can be toxic, ineffective, and be administered in an untimely manner. SHIELD will develop safe and effective broad-spectrum prophylaxes that will protect recipients from bloodborne bacteria and fungi and prevent BSI for up to 144 h. |
| Link to Additional Information: | SAM.gov Contract Opportunities |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
BAA Coordinator
SHIELD@darpa.mil Email:SHIELD@darpa.mil |
Related Documents
Folder 348974 Full Announcement-HR001123S0037 -> HR001123S0037.pdf
Folder 348974 Full Announcement-HR001123S0037 -> Attachment_2_HR001123S0037-SOW_Template.pdf
Folder 348974 Full Announcement-HR001123S0037 -> Attachment_1_HR001123S0037-Executive_Summary_Slide_Template.pdf
Folder 348974 Revised Full Announcement-HR001123S0037-Amendment-01 -> HR001123S0037-Amendment-01.pdf
Packages
| Agency Contact Information: | BAA Coordinator SHIELD@darpa.mil Email: SHIELD@darpa.mil |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 12.910 | PKG00282356 | Jul 25, 2023 | Sep 27, 2023 | View |
Package 1
Mandatory forms
348974 RR_SF424_5_0-5.0.pdf
348974 AttachmentForm_1_2-1.2.pdf
348974 RR_Budget10_3_0-3.0.pdf
348974 RR_KeyPersonExpanded_4_0-4.0.pdf
348974 RR_PersonalData_1_2-1.2.pdf
Optional forms
348974 SFLLL_2_0-2.0.pdf
348974 RR_SubawardBudget10_30_3_0-3.0.pdf
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