Opportunity ID: 331379

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-21-115
Funding Opportunity Title: Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 4
Posted Date: Feb 08, 2021
Last Updated Date: Nov 06, 2024
Original Closing Date for Applications: Jan 07, 2024
Current Closing Date for Applications: Nov 05, 2024
Archive Date: Dec 05, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: State governments
Special district governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Public housing authorities/Indian housing authorities
County governments
Independent school districts
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field’s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.

Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-21-115.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

Version History

Version Modification Description Updated Date
Update close date per reissued NOFO PAR-25-227. Nov 06, 2024
Changing close date per issuance of NOT-HD-24-001 Feb 08, 2021
Updating to correct close date Feb 08, 2021
Feb 08, 2021

DISPLAYING: Synopsis 4

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-21-115
Funding Opportunity Title: Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 4
Posted Date: Feb 08, 2021
Last Updated Date: Nov 06, 2024
Original Closing Date for Applications: Jan 07, 2024
Current Closing Date for Applications: Nov 05, 2024
Archive Date: Dec 05, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: State governments
Special district governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
City or township governments
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Public and State controlled institutions of higher education
Native American tribal organizations (other than Federally recognized tribal governments)
Public housing authorities/Indian housing authorities
County governments
Independent school districts
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field’s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.

Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-21-115.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Synopsis 3

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-21-115
Funding Opportunity Title: Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 3
Posted Date: Feb 08, 2021
Last Updated Date: Mar 07, 2024
Original Closing Date for Applications:
Current Closing Date for Applications: Jan 07, 2025
Archive Date: Feb 06, 2025
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
Public and State controlled institutions of higher education
State governments
For profit organizations other than small businesses
Special district governments
Independent school districts
City or township governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field’s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.

Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-21-115.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Synopsis 2

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-21-115
Funding Opportunity Title: Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 2
Posted Date: Feb 08, 2021
Last Updated Date: Jan 19, 2024
Original Closing Date for Applications:
Current Closing Date for Applications: May 07, 2024
Archive Date: Jun 06, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
Public and State controlled institutions of higher education
State governments
For profit organizations other than small businesses
Special district governments
Independent school districts
City or township governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description:

This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field’s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.

Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-21-115.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster

FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

DISPLAYING: Synopsis 1

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-21-115
Funding Opportunity Title: Natural History of Disorders Screenable in the Newborn Period (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Health
Income Security and Social Services
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.865 — Child Health and Human Development Extramural Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Feb 08, 2021
Last Updated Date: Feb 08, 2021
Original Closing Date for Applications:
Current Closing Date for Applications: Jan 07, 2024
Archive Date: Feb 12, 2024
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Public housing authorities/Indian housing authorities
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Small businesses
Native American tribal organizations (other than Federally recognized tribal governments)
Private institutions of higher education
Public and State controlled institutions of higher education
State governments
For profit organizations other than small businesses
Special district governments
Independent school districts
City or township governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: This funding opportunity announcement (FOA) encourages applications that propose to develop studies that will lead to a broad understanding of the natural history of disorders that already do or could potentially benefit from early identification by newborn screening. A comprehensive understanding of the natural history of a disorder has been identified as a necessary element to facilitate appropriate interventions for infants identified by newborn screening. By defining the sequence and timing of the onset of symptoms and complications of a disorder, a valuable resource will be developed for the field. In addition, for some disorders, specific genotype-phenotype correlations may allow prediction of the clinical course, and for other disorders, identification of modifying genetic, epigenetic, or environmental factors will enhance an understanding of the clinical outcomes for an individual with such a condition. Comprehensive data on natural history will facilitate the field’s ability to: 1) accurately diagnose the disorder; 2) understand the genetic and clinical heterogeneity and phenotypic expression of the disorder; 3) identify underlying mechanisms related to basic defects; 4) potentially prevent, manage, and treat symptoms and complications of the disorder; and 5) provide children and their families with needed support and predictive information about the disorder.
Link to Additional Information: http://grants.nih.gov/grants/guide/pa-files/PAR-21-115.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
Email:FBOWebmaster@OD.NIH.GOV

Folder 331379 Full Announcement-PAR-21-115 -> PAR-21-115-Full-Announcement.pdf

Packages

Agency Contact Information: NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
Email: FBOWebmaster@OD.NIH.GOV
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-F Use for due dates on or before January 24, 2022 PKG00265330 Jan 05, 2021 Jan 24, 2022 View
FORMS-G Use for due dates on or before January 24, 2023 PKG00269794 Oct 28, 2021 Jan 24, 2023 View
FORMS-H Use for due dates on or after January 25, 2023 PKG00277736 Nov 01, 2022 Nov 07, 2024 View

Package 1

Mandatory forms

331379 RR_SF424_2_0-2.0.pdf

331379 PHS398_CoverPageSupplement_5_0-5.0.pdf

331379 RR_OtherProjectInfo_1_4-1.4.pdf

331379 PerformanceSite_2_0-2.0.pdf

331379 RR_KeyPersonExpanded_2_0-2.0.pdf

331379 PHS398_ResearchPlan_4_0-4.0.pdf

331379 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf

Optional forms

331379 RR_Budget_1_4-1.4.pdf

331379 RR_SubawardBudget30_1_4-1.4.pdf

331379 PHS398_ModularBudget_1_2-1.2.pdf

331379 PHS_AssignmentRequestForm_3_0-3.0.pdf

Package 2

Mandatory forms

331379 RR_SF424_5_0-5.0.pdf

331379 PHS398_CoverPageSupplement_5_0-5.0.pdf

331379 RR_OtherProjectInfo_1_4-1.4.pdf

331379 PerformanceSite_4_0-4.0.pdf

331379 RR_KeyPersonExpanded_4_0-4.0.pdf

331379 PHS398_ResearchPlan_4_0-4.0.pdf

331379 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf

Optional forms

331379 RR_Budget_3_0-3.0.pdf

331379 RR_SubawardBudget30_3_0-3.0.pdf

331379 PHS398_ModularBudget_1_2-1.2.pdf

331379 PHS_AssignmentRequestForm_3_0-3.0.pdf

Package 3

Mandatory forms

331379 RR_SF424_5_0-5.0.pdf

331379 PHS398_CoverPageSupplement_5_0-5.0.pdf

331379 RR_OtherProjectInfo_1_4-1.4.pdf

331379 PerformanceSite_4_0-4.0.pdf

331379 RR_KeyPersonExpanded_4_0-4.0.pdf

331379 PHS398_ResearchPlan_5_0-5.0.pdf

331379 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf

Optional forms

331379 RR_Budget_3_0-3.0.pdf

331379 RR_SubawardBudget30_3_0-3.0.pdf

331379 PHS398_ModularBudget_1_2-1.2.pdf

331379 PHS_AssignmentRequestForm_3_0-3.0.pdf

2025-07-11T05:43:13-05:00

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