The Human Immunology Project Consortium (HIPC) offers this grant to characterize human immune responses to vaccinations, vaccine adjuvants, or natural infections, including HIV. This funding supports single institutions or consortia using high-throughput systems immunology and detailed clinical phenotyping. The purpose is to measure the diversity and commonalities of human immune responses longitudinally in well-characterized cohorts. Research will develop molecular signatures defining immune profiles and identify biomarkers correlating with vaccination or infection outcomes. A key goal is promoting rapid public access to HIPC-supported data and meta-data via portals such as ImmPort, facilitating advancements in human immunology research.
Opportunity ID: 331389
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-20-079 |
| Funding Opportunity Title: | Human Immunology Project Consortium (U19 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 08, 2021 |
| Last Updated Date: | Feb 08, 2021 |
| Original Closing Date for Applications: | Jun 04, 2021 |
| Current Closing Date for Applications: | Jun 04, 2021 |
| Archive Date: | Jul 10, 2021 |
| Estimated Total Program Funding: | $16,000,000 |
| Award Ceiling: | $1,500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses For profit organizations other than small businesses Special district governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) for the Human Immunology Project Consortium (HIPC) solicits applications from single institutions, or consortia of institutions, to participate in a network of human immunology profiling research groups in the area of infectious diseases, including HIV. The purpose of this FOA is to characterize human immune responses/mechanisms elicited by vaccinations, vaccine adjuvants or natural infections by capitalizing on recent advances in immune profiling technologies. Studies supported under this FOA will measure the diversity and commonalities of human immune responses under a variety of conditions and longitudinally using high-throughput systems immunology approaches coupled with detailed clinical phenotyping in well-characterized human cohorts. The resulting data will be used to develop molecular signatures that define immune response profiles and identify biomarkers that correlate with the outcomes of vaccinations, vaccine adjuvants or natural infections in humans. An additional goal of this program is to promote rapid public access to HIPC-supported data and meta-data through public portals such as ImmPort. A companion FOA will support development and operation of a HIPC Coordinating Center that will be responsible for fostering collaborations amongst HIPC-funded investigators; facilitating public dissemination of integrated HIPC findings and knowledge; and supporting development or adoption of new, robust methods for data integration, analysis, presentation, and visualization to further research and development in this field. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-20-079.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00265880 | May 04, 2021 | Jun 04, 2021 | View |
Package 1
Mandatory forms
331389 RR_SF424_2_0-2.0.pdf
331389 PHS398_CoverPageSupplement_5_0-5.0.pdf
331389 RR_OtherProjectInfo_1_4-1.4.pdf
331389 PerformanceSite_2_0-2.0.pdf
331389 RR_KeyPersonExpanded_2_0-2.0.pdf
331389 PHS398_ResearchPlan_4_0-4.0.pdf
331389 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
331389 PHS_Additional_IndirectCosts-1.0.pdf
331389 PHS_AssignmentRequestForm_3_0-3.0.pdf
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